Date published: 2025-12-17

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Acifluorfen (CAS 50594-66-6)

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Alternate Names:
5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid
Application:
Acifluorfen is an herbicide against broadleaf weeds
CAS Number:
50594-66-6
Molecular Weight:
361.66
Molecular Formula:
C14H7ClF3NO5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Acifluorfen is an herbicide against broadleaf weeds. Prevents plant photosynthetic activity by inhibiting the synthesis of chlorophyll. It also works by inhibiting acetolactate synthase activity which is involved in the biosynthesis of branched-chain amino acids. Acifluorfen has also been found to affect the reproductive process of plants by reducing fertility and seed production.


Acifluorfen (CAS 50594-66-6) References

  1. Overexpression of plastidic protoporphyrinogen IX oxidase leads to resistance to the diphenyl-ether herbicide acifluorfen.  |  Lermontova, I. and Grimm, B. 2000. Plant Physiol. 122: 75-84. PMID: 10631251
  2. Photochemistry and photoinduced toxicity of acifluorfen, a diphenyl-ether herbicide.  |  Scrano, L., et al. 2002. J Environ Qual. 31: 268-74. PMID: 11837431
  3. Homoglutathione confers tolerance to acifluorfen in transgenic tobacco plants expressing soybean homoglutathione synthetase.  |  Sugiyama, A. and Sekiya, J. 2005. Plant Cell Physiol. 46: 1428-32. PMID: 15937325
  4. Evidence from studies with acifluorfen for participation of a flavin-cytochrome complex in blue light photoreception for phototropism of oat coleoptiles.  |  Leong, TY. and Briggs, WR. 1982. Plant Physiol. 70: 875-81. PMID: 16662593
  5. Acifluorfen-induced isoflavonoids and enzymes of their biosynthesis in mature soybean leaves : whole leaf and mesophyll responses.  |  Cosio, EG., et al. 1985. Plant Physiol. 78: 14-9. PMID: 16664187
  6. Effects of Acifluorfen on Endogenous Antioxidants and Protective Enzymes in Cucumber (Cucumis sativus L.) Cotyledons.  |  Kenyon, WH. and Duke, SO. 1985. Plant Physiol. 79: 862-6. PMID: 16664506
  7. Crystal structure of protoporphyrinogen oxidase from Myxococcus xanthus and its complex with the inhibitor acifluorfen.  |  Corradi, HR., et al. 2006. J Biol Chem. 281: 38625-33. PMID: 17046834
  8. Evaluation of the carcinogenic potential of pesticides. 1. Acifluorfen.  |  Quest, JA., et al. 1989. Regul Toxicol Pharmacol. 10: 149-59. PMID: 2813868
  9. Rapid sonochemical synthesis of silver nano-leaves encapsulated on iron pyrite nanocomposite: An excellent catalytic application in the electrochemical detection of herbicide (Acifluorfen).  |  Chen, TW., et al. 2019. Ultrason Sonochem. 54: 90-98. PMID: 30846281
  10. Altered regulation of porphyrin biosynthesis and protective responses to acifluorfen-induced photodynamic stress in transgenic rice expressing Bradyrhizobium japonicum Fe-chelatase.  |  Tran, BQ., et al. 2019. Pestic Biochem Physiol. 159: 1-8. PMID: 31400771
  11. Preparation of Acifluorfen-Based Ionic Liquids with Fluorescent Properties for Enhancing Biological Activities and Reducing the Risk to the Aquatic Environment.  |  Tang, G., et al. 2020. J Agric Food Chem. 68: 6048-6057. PMID: 32392059
  12. Stable Fluorescent Nanoparticles Based on Co-assembly of Acifluorfen and Poly(salicylic acid) for Enhancing Herbicidal Activity and Reducing Environmental Risks.  |  Wang, H., et al. 2023. ACS Appl Mater Interfaces. 15: 4303-4314. PMID: 36631294
  13. Generation of resistance to the diphenyl ether herbicide acifluorfen by MEL cells.  |  Prasad, AR. and Dailey, HA. 1995. Biochem Biophys Res Commun. 215: 186-91. PMID: 7575589

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Acifluorfen, 50 mg

sc-239196
50 mg
$64.00