Ac-VEID-pNA, Colorimetric Substrate is a colorimetric substrate for caspase-6 (Km=30μM; Kcat/Km=168,000 M-1sec-1) and related cysteine proteases. The sequence is based on the lamin A site of cleavage. Cleavage of the substrate by a caspase results in the release of pNA, which can be detected by its absorbance at 405nm (ε=10,500 M-1cm-1).
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See how others have used Ac-VEID-pNA, Colorimetric Substrate (CAS 189684-54-6). Click on the entry to view the PubMed entry .
PMID: # 30795621 Nováková, J.|Talacko, P.|Novák, P.|Vališ, K.| et al. 2019. Cells. 8:
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