Date published: 2025-10-2

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ABT 263-d8 (CAS 1217620-38-6)

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Application:
ABT 263-d8 is a potent inhibitor of antiapoptotic Bcl-2 proteins and potential anticancer agent
CAS Number:
1217620-38-6
Molecular Weight:
982.66
Molecular Formula:
C47H47D8ClF3N5O6S3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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ABT 263-d8, also known as Navitoclax-d8, is a deuterated variant of Navitoclax designed to enhance biochemical studies related to apoptosis. By inhibiting Bcl-2 family proteins, key players in the regulation of cell death, it provides a valuable resource for probing the mechanisms underlying apoptosis. The substitution of hydrogen atoms with deuterium not only modifies its properties for experimental advantage but also improves the molecule′s detection and measurement in studies, thus enriching our comprehension of its action and the broader implications for cellular life and death processes. ABT 263-d8′s role is in research aimed at uncovering the functions and impact of Bcl-2 family proteins on cellular dynamics, strictly within non-clinical research environments.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

ABT 263-d8, 1 mg

sc-217551
1 mg
$398.00

ABT 263-d8, 10 mg

sc-217551A
10 mg
$2856.00