Molecular structure of AACOCH3
AACOCH3
Application:
AACOCH3 is a negative control for AACOCF31,2 and stimulator of AA release
Molecular Weight:
302.5
Molecular Formula:
C21H34O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
AACOCH3 is used as a negative control for AACOCF3 but stimulates AA release by way of possible inhibitor of metabolizing or uptake enzymes, or via direct stimulation of PLA2.
AACOCH3 References
- Secretory and cytosolic phospholipase A(2)regulate the long-term cytokine-induced eicosanoid production in human keratinocytes. | Sjursen, W., et al. 2000. Cytokine. 12: 1189-94. PMID: 10930295
- Acanthamoeba-cytopathic protein induces apoptosis and proinflammatory cytokines in human corneal epithelial cells by cPLA2α activation. | Tripathi, T., et al. 2012. Invest Ophthalmol Vis Sci. 53: 7973-82. PMID: 23132804
- Significance of arachidonic acid in ocular infections and inflammation. | Tripathi, T. and Alizadeh, H. 2014. Inflamm Cell Signal. 1: PMID: 26082934
- Activation of a novel form of phospholipase A2 during liver regeneration. | Wojtaszek, PA., et al. 1995. FEBS Lett. 367: 228-32. PMID: 7607312
- Characterization of a novel phospholipase A2 activity in human brain. | Ross, BM., et al. 1995. J Neurochem. 64: 2213-21. PMID: 7722506
- Multiple enzymatic activities of the human cytosolic 85-kDa phospholipase A2: hydrolytic reactions and acyl transfer to glycerol. | Hanel, AM. and Gelb, MH. 1995. Biochemistry. 34: 7807-18. PMID: 7794891
- Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2. | Street, IP., et al. 1993. Biochemistry. 32: 5935-40. PMID: 8018213
- Characterization of interfacial catalysis by Aeromonas hydrophila lipase/acyltransferase in the highly processive scooting mode. | Jain, MK., et al. 1994. Biochemistry. 33: 5011-20. PMID: 8172876
- Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. | Riendeau, D., et al. 1994. J Biol Chem. 269: 15619-24. PMID: 8195210
- Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1. | Thommesen, L., et al. 1998. J Immunol. 161: 3421-30. PMID: 9759860
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AACOCH3, 10 mg | sc-205590 | 10 mg | $53.00 | |||
AACOCH3, 50 mg | sc-205590A | 50 mg | $285.00 |