9(S)-HODE-d4 (CAS 98524-19-7 (unlabeled))

9(S)-HODE-d4, with the CAS number 98524-19-7, is a deuterated form of 9(S)-hydroxyoctadecadienoic acid (9(S)-HODE), a primary oxidation product of linoleic acid and a member of the hydroxyoctadecadienoic acids. The introduction of four deuterium atoms in place of hydrogen enhances the molecular stability and detectability of this compound, making it particularly useful in sophisticated analytical studies such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. In research, 9(S)-HODE-d4 serves as an important tool for investigating the detailed metabolic pathways of lipid oxidation and the biological roles of 9(S)-HODE. This molecule participates in the modulation of diverse biological processes, including cell signaling and the regulation of inflammatory responses. Studies utilizing 9(S)-HODE-d4 focus on its formation from linoleic acid through enzymatic pathways involving lipoxygenases, and its subsequent interactions with specific receptors and signaling molecules within cells. This research helps in understanding the complex dynamics of lipid peroxidation products in cellular environments and their potential roles in regulating cellular functions and responses to oxidative stress. The use of the deuterated version allows researchers to trace and quantify the dynamics of these interactions with greater precision, providing clearer insights into the bioactive mechanisms of lipid mediators.