Molecular structure of 8(R),15(S)-DiHETE, CAS Number: 80234-67-9
8(R),15(S)-DiHETE (CAS 80234-67-9)
Application:
8(R),15(S)-DiHETE is a sensitizer for C-fiber mechanoheat nociceptors
CAS Number:
80234-67-9
Molecular Weight:
336.5
Molecular Formula:
C20H32O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
8(R),15(S)-DiHETE produces a dose-dependent hyperalgesia2. Stereospecifically sensitizes C-fiber mechanoheat nociceptors.1 See 15-Lipoxygenase pathway for structure.
8(R),15(S)-DiHETE (CAS 80234-67-9) References
- The 15-lipoxygenase product, 8R,15S-diHETE, stereospecifically sensitizes C-fiber mechanoheat nociceptors in hairy skin of rat. | White, DM., et al. 1990. J Neurophysiol. 63: 966-70. PMID: 2162922
- Hyperalgesic properties of 15-lipoxygenase products of arachidonic acid. | Levine, JD., et al. 1986. Proc Natl Acad Sci U S A. 83: 5331-4. PMID: 3014543
- Mechanisms of leukotriene formation: hemoglobin-catalyzed transformation of 15-HPETE into 8,15-DiHETE and 14,15-DiHETE isomers. | Sok, DE., et al. 1983. Biochem Biophys Res Commun. 110: 273-9. PMID: 6301444
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8(R),15(S)-DiHETE, 50 µg | sc-200425 | 50 µg | $196.00 |