8-Oxo-Benzylguanine (CAS 158754-46-2)
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8-Oxo-Benzylguanine is a chemical compound with applications in biochemistry and molecular biology. It is a derivative of benzylguanine, a simple aromatic compound that contains a reactive guanine group. One area of research on 8-Oxo-Benzylguanine is its use as a substrate for the enzyme alkylguanine DNA alkyltransferase (AGT). AGT is a DNA repair enzyme that plays a critical role in protecting cells from the effects of alkylating agents. By reacting with 8-Oxo-Benzylguanine, AGT can be inactivated, researchers have investigated the use of 8-Oxo-Benzylguanine as a building block for the synthesis of oligonucleotides. Because 8-Oxo-Benzylguanine is a relatively simple aromatic compound, it can be used to investigate fundamental chemical processes, such as nucleophilic substitution reactions, in a controlled setting.
8-Oxo-Benzylguanine (CAS 158754-46-2) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-Oxo-Benzylguanine, 50 mg | sc-478298 | 50 mg | $394.00 |