Date published: 2025-12-30

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(−)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine (CAS 139628-16-3)

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Application:
(−)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine is a chiral oxidizing agent for proteomics research
CAS Number:
139628-16-3
Molecular Weight:
298.19
Molecular Formula:
C10H13Cl2NO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(−)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine, referred to as DCCO, is a versatile and potent organic compound extensively utilized in organic synthesis and pharmaceutical development. Derived from natural camphor, DCCO serves as a valuable reagent in laboratory applications, offering a broad range of applications. DCCO finds utility in scientific and medical research, contributing to the synthesis of new drugs, the exploration of drug delivery systems, and the investigation of biochemical and physiological processes. The multifaceted applications of (−)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine encompass diverse scientific realms. Notably, it is utilized as a reagent to synthesize complex molecules, including antibiotics and hormones, while also facilitating the development of novel pharmaceuticals. Furthermore, it aids in examining biochemical and physiological processes, such as gene expression regulation, cell proliferation control, and protein synthesis inhibition. Additionally, (−)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine serves as useful to study the impact of drugs on the central nervous system. Although the precise mechanism of action remains incompletely understood, it is postulated that (−)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine acts as a nucleophilic reagent, engaging with various molecules like proteins, carbohydrates, and lipids. Specifically, its interaction with proteins involves the formation of covalent bonds with amino acid side chains, consequently influencing protein structure, function, and subsequently impacting cellular processes.


(−)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine (CAS 139628-16-3) References

  1. Selective monosulfoxidation of tetrathiafulvalenes into chiral TTF-sulfoxides.  |  Chas, M., et al. 2009. Chirality. 21: 818-25. PMID: 19205039
  2. Effect of aggregation on stereochemistry and mechanism of asymmetric oxidation of the lithium enolate of methyl 3,3-dimethylbutanoate in the solid state and in solution  |  Yen Wei ∗R. Bakthavatchalam. 4 June 1993,. Tetrahedron Letters. Volume 34, Issue 23,: Pages 3715-3718.
  3. Synthetic studies on (1S)-1-(6,7-dimethoxy-2-naphthyl)-1-(1H-imidazol-4-yl)-2-methylpropan-1-ol as a selective C17,20-lyase inhibitor  |  Nobuyuki Matsunaga. 5 July 2004,. Tetrahedron: Asymmetry. Volume 15, Issue 13,: Pages 2021-2028.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(−)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine, 5 g

sc-396622
5 g
$234.00