Date published: 2025-10-20

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7-Methyluric Acid (CAS 612-37-3)

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Alternate Names:
7,9-Dihydro-7-methyl-1H-purine-2,6,8(3H)-trione; N7-Methyluric Acid
Application:
7-Methyluric Acid is a metabolite of Theobromine
CAS Number:
612-37-3
Molecular Weight:
182.14
Molecular Formula:
C6H6N4O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-Methyluric Acid is a metabolite of Theobromine (sc-203296). Through the use of high performance liquid chromatography and capillary electrophoresis it has been determined that 7-Methyluric Acid constitiutes approximately 2% of the metabolites found in urinary excretion after Theobromine metabolism.


7-Methyluric Acid (CAS 612-37-3) References

  1. Use of novel solid-phase extraction sorbent materials for high-performance liquid chromatography quantitation of caffeine metabolism products methylxanthines and methyluric acids in samples of biological origin.  |  Georgia, KA., et al. 2001. J Chromatogr B Biomed Sci Appl. 759: 209-18. PMID: 11499474
  2. Methylated purines in urinary stones.  |  Safranow, K. and Machoy, Z. 2005. Clin Chem. 51: 1493-8. PMID: 15919878
  3. Identification of Urinary Metabolite Biomarkers of Type 2 Diabetes Nephropathy Using an Untargeted Metabolomic Approach.  |  Chen, CJ., et al. 2018. J Proteome Res. 17: 3997-4007. PMID: 30265543
  4. The association between caffeine intake and testosterone: NHANES 2013-2014.  |  Glover, FE., et al. 2022. Nutr J. 21: 33. PMID: 35578259
  5. 7-Methylxanthine Inhibits the Formation of Monosodium Urate Crystals by Increasing Its Solubility.  |  Costa-Bauza, A. and Grases, F. 2023. Biomolecules. 13: PMID: 38136640
  6. Association between caffeine metabolites in urine and muscle strength in young and older adults: A cross-sectional study from NHANES 2011-2012.  |  Batista-da-Silva, B., et al. 2024. Clin Nutr. 43: 1584-1592. PMID: 38759491
  7. Comparison of the urinary metabolite profile of caffeine in young and elderly males.  |  Blanchard, J., et al. 1985. Br J Clin Pharmacol. 19: 225-32. PMID: 3986081
  8. Theobromine kinetics and metabolic disposition.  |  Tarka, SM., et al. 1983. Clin Pharmacol Ther. 34: 546-55. PMID: 6617078
  9. Determination of caffeine and its metabolites in urine by high-performance liquid chromatography and capillary electrophoresis.  |  Rodopoulos, N. and Norman, A. 1994. Scand J Clin Lab Invest. 54: 305-15. PMID: 7939374
  10. Elimination of theobromine metabolites in healthy adults.  |  Rodopoulos, N., et al. 1996. Scand J Clin Lab Invest. 56: 373-83. PMID: 8837245

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Methyluric Acid, 5 mg

sc-210642
5 mg
$260.00