Date published: 2025-10-18

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7-Hydroxyquinoline (CAS 580-20-1)

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CAS Number:
580-20-1
Purity:
≥97%
Molecular Weight:
145.16
Molecular Formula:
C9H7NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-Hydroxyquinoline is an aromatic heterocyclic compound characterized by the presence of both a nitrogen and oxygen atom. It serves as a reagent in organic synthesis and has garnered attention for its potential applications in biochemistry and molecular biology. Acting as a chelating agent, 7-Hydroxyquinoline exhibits the ability to bind to various metal ions, including iron, copper, and zinc. Through this binding process, it hinders the participation of these metal ions in biochemical reactions, effectively impeding the growth of bacteria and fungi.


7-Hydroxyquinoline (CAS 580-20-1) References

  1. Grotthus-type and diffusive proton transfer in 7-hydroxyquinoline.(NH(3))(n) clusters.  |  Meuwly, M., et al. 2001. J Am Chem Soc. 123: 11446-53. PMID: 11707122
  2. Steady state and time-resolved spectroscopic studies of 7-hydroxyquinoline in various polymeric matrices.  |  Mehata, MS., et al. 2002. Spectrochim Acta A Mol Biomol Spectrosc. 58: 1589-98. PMID: 12166730
  3. Biphasic tautomerization dynamics of excited 7-hydroxyquinoline in reverse micelles.  |  Kwon, OH., et al. 2006. J Phys Chem B. 110: 11997-2004. PMID: 16800508
  4. Excited-state proton-transfer dynamics of 7-hydroxyquinoline in room temperature ionic liquids.  |  Bhattacharya, B. and Samanta, A. 2008. J Phys Chem B. 112: 10101-6. PMID: 18661938
  5. Photoinduced hydrogen-atom eliminations of 6-hydroxyquinoline and 7-hydroxyquinoline studied by low-temperature matrix-isolation infrared spectroscopy and density-functional-theory calculations.  |  Sekine, M., et al. 2009. J Phys Chem A. 113: 8286-98. PMID: 19569673
  6. Solvent effect on the excited-state proton transfer of 7-hydroxyquinoline along a hydrogen-bonded ethanol dimer.  |  Kang, B., et al. 2011. Phys Chem Chem Phys. 13: 6332-9. PMID: 21359346
  7. Excited-state proton-relay dynamics of 7-hydroxyquinoline controlled by solvent reorganization in room temperature ionic liquids.  |  Lim, H., et al. 2012. Phys Chem Chem Phys. 14: 218-24. PMID: 22073404
  8. Direct observation of conformation-dependent pathways in the excited-state proton transfer of 7-hydroxyquinoline in bulk alcohols.  |  Park, SY., et al. 2012. J Phys Chem B. 116: 14153-8. PMID: 23157383
  9. Combined Experimental and Theoretical Study of the Transient IR Spectroscopy of 7-Hydroxyquinoline in the First Electronically Excited Singlet State.  |  Hoffmann, F., et al. 2016. J Phys Chem A. 120: 9378-9389. PMID: 27934323
  10. 8-(Pyridin-2-yl)quinolin-7-ol as a Platform for Conjugated Proton Cranes: A DFT Structural Design.  |  Georgiev, A. and Antonov, L. 2020. Micromachines (Basel). 11: PMID: 33003325
  11. Acylhydrazone Subunits as a Proton Cargo Delivery System in 7-Hydroxyquinoline.  |  Nakashima, K., et al. 2021. Chemistry. 27: 11559-11566. PMID: 34137094
  12. Characterization of fluorescent probe substrates to develop an efficient high-throughput assay for neonatal hepatic CYP3A7 inhibition screening.  |  Work, HM., et al. 2021. Sci Rep. 11: 19443. PMID: 34593846
  13. Solvent-Triggered Long-Range Proton Transport in 7-Hydroxyquinoline Using a Sulfonamide Transporter Group.  |  Nakashima, K., et al. 2022. J Org Chem. 87: 6794-6806. PMID: 35512011
  14. Long-Range Proton Transfer in 7-Hydroxy-Quinoline-Based Azomethine Dyes: A Hidden Reason for the Low Efficiency.  |  Rode, MF., et al. 2022. Molecules. 27: PMID: 36500317
  15. Ultrafast Proton Transfer Pathways Mediated by Amphoteric Imidazole.  |  Codescu, MA., et al. 2023. J Phys Chem Lett. 14: 4775-4785. PMID: 37186569

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Hydroxyquinoline, 1 g

sc-311267
1 g
$92.00

7-Hydroxyquinoline, 5 g

sc-311267A
5 g
$257.00