Date published: 2025-10-19

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7-(Diethylamino)coumarin-3-carbohydrazide (CAS 100343-98-4)

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Application:
7-(Diethylamino)coumarin-3-carbohydrazide is derivatizing agent for detection of carboxylic acids
CAS Number:
100343-98-4
Purity:
≥95%
Molecular Weight:
275.30
Molecular Formula:
C14H17N3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-(Diethylamino)coumarin-3-carbohydrazide, also known as DECC, is a remarkably versatile and valuable chemical compound. As a derivative of coumarin, it finds extensive utility across various scientific applications, including organic synthesis. 7-(Diethylamino)coumarin-3-carbohydrazide possesses water solubility and ease of synthesis, rendering it a favored choice for research endeavors. Within scientific research, 7-(Diethylamino)coumarin-3-carbohydrazide exhibits a broad range of applications. It serves as a fluorescent probe in biochemical and physiological experiments, owing to its exceptional sensitivity to pH alterations in aqueous solutions. Consequently, it facilitates the detection of pH changes due to its pronounced pH-dependent fluorescent properties. Furthermore, 7-(Diethylamino)coumarin-3-carbohydrazide serves as an energy source for cellular metabolism, making it an ideal substrate for enzymatic reactions. In the realm of organic synthesis, it acts as a valuable reagent for the synthesis of other compounds. The fluorescence of 7-(Diethylamino)coumarin-3-carbohydrazide arises from its ability to absorb light at a specific wavelength and emit light at a different wavelength. This phenomenon stems from its capability to undergo a conformational change in response to varying pH conditions. As the pH of the solution decreases, the fluorescent intensity of 7-(Diethylamino)coumarin-3-carbohydrazide increases, enabling its reliable deployment as an indicator of pH changes.


7-(Diethylamino)coumarin-3-carbohydrazide (CAS 100343-98-4) References

  1. Simultaneous detection of low and high molecular weight carbonylated compounds derived from lipid peroxidation by electrospray ionization-tandem mass spectrometry.  |  Milic, I., et al. 2013. Anal Chem. 85: 156-62. PMID: 23186270
  2. Derivatization and detection of small aliphatic and lipid-bound carbonylated lipid peroxidation products by ESI-MS.  |  Milic, I. and Fedorova, M. 2015. Methods Mol Biol. 1208: 3-20. PMID: 25323495
  3. Identification of carbonylated lipids from different phospholipid classes by shotgun and LC-MS lipidomics.  |  Ni, Z., et al. 2015. Anal Bioanal Chem. 407: 5161-73. PMID: 25701423
  4. Selective labeling for the identification and semi-quantification of lipid aldehydes in food products.  |  Hollebrands, B., et al. 2018. Anal Bioanal Chem. 410: 5421-5429. PMID: 29744561
  5. A novel fluorimetric assay for visualization and quantification of protein carbonyls in muscle foods.  |  Cropotova, J. and Rustad, T. 2019. Food Chem. 297: 125006. PMID: 31253309
  6. Spectroscopic Investigation of DCCH and FTSC as a potential pair for Förster Resonance Energy Transfer in different solvents.  |  Urstöger, G., et al. 2020. PLoS One. 15: e0228543. PMID: 32045426

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-(Diethylamino)coumarin-3-carbohydrazide, 25 mg

sc-214392
25 mg
$198.00