Date published: 2025-10-20

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7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin (CAS 76877-34-4)

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Application:
7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin is a fluorescent thiol-reactive neutral probe
CAS Number:
76877-34-4
Molecular Weight:
490.33
Molecular Formula:
C22H23IN2O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin stands as a synthetic compound that holds remarkable applications in scientific research. Initially synthesized in the early 2000s, this versatile compound has since been widely employed in numerous experiments and studies, delving into its diverse biochemical and physiological effects. Researchers across various scientific fields, ranging from pharmacology to biochemistry, have harnessed its potency, making it an invaluable tool for their investigations. In the realms of pharmacology and biochemistry, 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin has been extensively utilized to examine the impacts of drugs and other compounds on the body. Furthermore, it has proven instrumental in investigating the biochemical and physiological effects of a wide array of compounds, offering valuable insights in these scientific domains. Notably, this compound has played a significant role in exploring the effects of environmental pollutants on the body, further expanding its utility. As for the mechanism of action, a comprehensive understanding of 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin is yet to be attained. It is believed to potentially function as a competitive inhibitor of specific enzymes, such as cytochrome P450 enzymes, which play a role in the metabolism of drugs and other compounds. Additionally, it may serve as an agonist or antagonist for certain receptors, such as G-protein coupled receptors, essential in signal transduction pathways. Through its multifaceted properties and effectiveness in laboratory experiments, 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin remains an indispensable asset for researchers across scientific disciplines, aiding in the advancement of scientific knowledge and discoveries.


7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin (CAS 76877-34-4) References

  1. Ultra-performance liquid chromatographic determination of L-ergothioneine in commercially available classes of cow milk.  |  Sotgia, S., et al. 2014. J Food Sci. 79: C1683-7. PMID: 25154712
  2. Amniotic fluid l-ergothioneine concentrations in pregnant sheep after natural mating and transfer of vitrified/thawed in-vitro produced embryos.  |  Sotgia, S., et al. 2015. Res Vet Sci. 102: 238-41. PMID: 26412552
  3. Simultaneous determination of the main amino thiol and thione in human whole blood by CE and LC.  |  Sotgia, S., et al. 2016. Bioanalysis. 8: 945-51. PMID: 27067265
  4. Fluorescent Peptide Dendrimers for siRNA Transfection: Tracking pH Responsive Aggregation, siRNA Binding, and Cell Penetration.  |  Heitz, M., et al. 2020. Bioconjug Chem. 31: 1671-1684. PMID: 32421327
  5. The current status of biotechnological production and the application of a novel antioxidant ergothioneine.  |  Han, Y., et al. 2021. Crit Rev Biotechnol. 41: 580-593. PMID: 33550854
  6. Determination of L-Ergothioneine in Cosmetics Based on Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry.  |  Liu, L., et al. 2022. Int J Anal Chem. 2022: 4372295. PMID: 36204714

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin, 10 mg

sc-210607
10 mg
$105.00