Molecular structure of 6-Methylmercaptopurine riboside, CAS Number: 342-69-8
6-Methylmercaptopurine riboside (CAS 342-69-8)
Application:
6-Methylmercaptopurine riboside is a chemical used to study thiopurine metabolism by enzymes
CAS Number:
342-69-8
Purity:
≥98%
Molecular Weight:
298.32
Molecular Formula:
C11H14N4O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
6-Methylmercaptopurine riboside is a purine nucleoside analog that functions as an antimetabolite. It inhibits the synthesis of nucleic acids by interfering with the synthesis of DNA and RNA. 6-Methylmercaptopurine Riboside is incorporated into the DNA and RNA of rapidly dividing cells, leading to the disruption of nucleic acid metabolism. 6-Methylmercaptopurine riboside acts as a competitive inhibitor of hypoxanthine-guanine phosphoribosyltransferase, an enzyme involved in the salvage pathway of purine synthesis. By inhibiting this enzyme, it disrupts the production of purine nucleotides, which are for DNA and RNA synthesis. This disruption ultimately leads to the inhibition of cell growth and proliferation. 6-Methylmercaptopurine riboside may induce apoptosis in certain cell types, further contributing to its anti-proliferative effects.
6-Methylmercaptopurine riboside (CAS 342-69-8) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-Methylmercaptopurine riboside, 1 g | sc-221106 | 1 g | $420.00 |