Date published: 2025-11-2

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6-Hydrazinonicotinic acid (CAS 133081-24-0)

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CAS Number:
133081-24-0
Molecular Weight:
153.14
Molecular Formula:
C6H7N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Hydrazinonicotinic acid (HNA) is a white crystalline solid, belonging to the hydrazine family of organic compounds. It is soluble in both water and organic solvents. 6-Hydrazinonicotinic acid finds extensive use in scientific research, serving as a versatile tool for various purposes. One primary application of 6-Hydrazinonicotinic acid in scientific research is its role as a reagent in organic synthesis. It effectively aids in the production of diverse compounds, including 6-hydrazino-nicotinic acid esters, 6-hydrazino-nicotinic acid amides, and 6-hydrazino-nicotinic acid derivatives.


6-Hydrazinonicotinic acid (CAS 133081-24-0) References

  1. A novel ternary ligand system useful for preparation of cationic (99m)Tc-diazenido complexes and (99m)Tc-labeling of small biomolecules.  |  Kim, YS., et al. 2006. Bioconjug Chem. 17: 473-84. PMID: 16536480
  2. Chemoselective hydrazone formation between HYNIC-functionalized peptides and (18)F-fluorinated aldehydes.  |  Bruus-Jensen, K., et al. 2006. Nucl Med Biol. 33: 173-83. PMID: 16546671
  3. Preparation of hydrazino-modified proteins and their use for the synthesis of 99mTc-protein conjugates.  |  Schwartz, DA., et al. 1991. Bioconjug Chem. 2: 333-6. PMID: 1838699
  4. Targeting of lectinlike oxidized low-density lipoprotein receptor 1 (LOX-1) with 99mTc-labeled anti-LOX-1 antibody: potential agent for imaging of vulnerable plaque.  |  Ishino, S., et al. 2008. J Nucl Med. 49: 1677-85. PMID: 18794262
  5. Imaging with radiolabelled anti-membrane type 1 matrix metalloproteinase (MT1-MMP) antibody: potentials for characterizing atherosclerotic plaques.  |  Kuge, Y., et al. 2010. Eur J Nucl Med Mol Imaging. 37: 2093-104. PMID: 20625725
  6. Tissue factor detection for selectively discriminating unstable plaques in an atherosclerotic rabbit model.  |  Temma, T., et al. 2010. J Nucl Med. 51: 1979-86. PMID: 21078793
  7. Synthesis and evaluation of analogues of HYNIC as bifunctional chelators for technetium.  |  Meszaros, LK., et al. 2011. Dalton Trans. 40: 6260-7. PMID: 21350776
  8. Hydrazinonicotinic acid as a novel matrix for highly sensitive and selective MALDI-MS analysis of oligosaccharides.  |  Jiao, J., et al. 2015. Analyst. 140: 156-61. PMID: 25360446
  9. Novel tetrahydroacridine derivatives inhibit human lung adenocarcinoma cell growth by inducing G1 phase cell cycle arrest and apoptosis.  |  Olszewska, P., et al. 2014. Biomed Pharmacother. 68: 959-67. PMID: 25458793
  10. Derivatizations of Sgc8-c aptamer to prepare metallic radiopharmaceuticals as imaging diagnostic agents: Syntheses, isolations, and physicochemical characterizations.  |  Sicco, E., et al. 2018. Chem Biol Drug Des. 91: 747-755. PMID: 29080264
  11. The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist.  |  Abiraj, K., et al. 2018. EJNMMI Res. 8: 75. PMID: 30069789
  12. Facile synthesis of rapamycin-peptide conjugates as mTOR and Akt inhibitors.  |  Singh, S., et al. 2021. Org Biomol Chem. 19: 4352-4358. PMID: 33908567
  13. Bifunctional NHS-BAT ester for antibody conjugation and stable technetium-99m labeling: conjugation chemistry, immunoreactivity and kit formulation.  |  Eisenhut, M., et al. 1996. J Nucl Med. 37: 362-70. PMID: 8667077

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Hydrazinonicotinic acid, 250 mg

sc-278515
250 mg
$202.00