Date published: 2025-12-14

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6-Chloro-7-deazapurine-β-D-riboside (CAS 16754-80-6)

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Application:
6-Chloro-7-deazapurine-β-D-riboside is an ADK (adenosine kinase) inhibitor
CAS Number:
16754-80-6
Molecular Weight:
285.68
Molecular Formula:
C11H12ClN3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Chloro-7-deazapurine-β-D-riboside is a compound of interest in nucleoside chemistry and biochemical research. This chemical exhibits specific mechanisms of action related to its role as a nucleoside analog and its potential applications in nucleic acid modification studies. One notable mechanism involves its incorporation into nucleic acids, where it can replace natural nucleosides during DNA or RNA synthesis. This property has been leveraged in research aimed at studying DNA replication, transcription, and translation processes. Additionally, 6-Chloro-7-deazapurine-β-D-riboside has been investigated for its potential as a substrate or inhibitor of various enzymes involved in nucleic acid metabolism, such as DNA polymerases, RNA polymerases, and nucleoside kinases. Furthermore, this compound has been explored as a precursor in the synthesis of modified nucleotides and nucleic acid probes for applications in molecular biology, biotechnology, and diagnostic assays. Its unique structural features make it an attractive target for chemical synthesis and structural modification, enabling the development of novel nucleoside analogs with improved properties or enhanced biological activities. Overall, 6-Chloro-7-deazapurine-β-D-riboside serves as a valuable tool in nucleoside chemistry research, facilitating the investigation of nucleic acid structure-function relationships and the development of new strategies for nucleic acid manipulation and analysis.


6-Chloro-7-deazapurine-β-D-riboside (CAS 16754-80-6) References

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  3. Inhibition of nucleoside transport by new analogues of 4-nitrobenzylthioinosine: replacement of the ribose moiety by substituted benzyl groups.  |  Tromp, RA., et al. 2004. J Med Chem. 47: 5441-50. PMID: 15481982
  4. Targeting DHFR in parasitic protozoa.  |  Anderson, AC. 2005. Drug Discov Today. 10: 121-8. PMID: 15718161

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Chloro-7-deazapurine-β-D-riboside, 25 mg

sc-221096
25 mg
$235.00