Molecular structure of 6-Chloro-7-deazapurine, CAS Number: 3680-69-1
6-Chloro-7-deazapurine (CAS 3680-69-1)
CAS Number:
3680-69-1
Molecular Weight:
153.57
Molecular Formula:
C6H4ClN3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
6-Chloro-7-deazapurine functions as a purine analog. It acts as a competitive inhibitor of enzymes involved in purine metabolism, disrupting the synthesis of nucleic acids and leading to the inhibition of DNA and RNA replication. 6-Chloro-7-Deazapurine interferes with the normal cellular processes by incorporating itself into nucleic acids, ultimately disrupting their function. By doing so, it can be used to study the effects of purine analogs on cellular processes and to investigate the mechanisms of action of enzymes involved in purine metabolism. 6-Chloro-7-deazapurine may have an impact on cell growth and proliferation, which may be useful for studying the regulation of these processes at the molecular level.
6-Chloro-7-deazapurine (CAS 3680-69-1) References
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- Synthesis and cytostatic and antiviral activities of 2'-deoxy-2',2'-difluororibo- and 2'-deoxy-2'-fluororibonucleosides derived from 7-(Het)aryl-7-deazaadenines. | Perlíková, P., et al. 2013. ChemMedChem. 8: 832-46. PMID: 23559483
- Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K). | Lawhorn, BG., et al. 2015. J Med Chem. 58: 7431-48. PMID: 26355916
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- Design, synthesis, and biological evaluation of novel 7-deazapurine nucleoside derivatives as potential anti-dengue virus agents. | Lin, C., et al. 2018. Antiviral Res. 149: 95-105. PMID: 29129706
- Glycosylation of Pyrrolo[2,3- d]pyrimidines with 1- O-Acetyl-2,3,5-tri- O-benzoyl-β-d-ribofuranose: Substituents and Protecting Groups Effecting the Synthesis of 7-Deazapurine Ribonucleosides. | Ingale, SA., et al. 2018. J Org Chem. 83: 8589-8595. PMID: 29911384
- Synthesis of 7-trifluoromethyl-7-deazapurine ribonucleoside analogs and their monophosphate prodrugs. | Cho, JH., et al. 2020. Nucleosides Nucleotides Nucleic Acids. 39: 671-687. PMID: 31588837
- Iron/Copper Co-Catalyzed Cross-Coupling Reaction for the Synthesis of 6-Substituted 7-Deazapurines and the Corresponding Nucleosides. | Li, Q., et al. 2020. J Org Chem. 85: 403-418. PMID: 31858795
- A Potent and Selective Janus Kinase Inhibitor with a Chiral 3D-Shaped Triquinazine Ring System from Chemical Space. | Meier, K., et al. 2021. Angew Chem Int Ed Engl. 60: 2074-2077. PMID: 32986914
- Preparation and characterization of glucose-based covalent organic polymer coated silica as stationary phase for high-performance liquid chromatography. | Gao, L., et al. 2023. J Chromatogr A. 1693: 463876. PMID: 36857980
- Competing interests during the key N-glycosylation of 6-chloro-7-deaza-7-iodopurine for the synthesis of 7-deaza-2'-methyladenosine using Vorbrüggen conditions. | Naciuk, FF., et al. 2023. Front Chem. 11: 1163486. PMID: 37035111
- Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides | Klečka, M., Slavětínská, L. P., Tloušťová, E., Džubák, P., Hajdúch, M., & Hocek, M. 2015. MedChemComm. 6(4): 576-580.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-Chloro-7-deazapurine, 1 g | sc-217325 | 1 g | $40.00 | |||
6-Chloro-7-deazapurine, 5 g | sc-217325A | 5 g | $188.00 | |||
6-Chloro-7-deazapurine, 25 g | sc-217325B | 25 g | $460.00 | |||
6-Chloro-7-deazapurine, 100 g | sc-217325C | 100 g | $1140.00 |