Molecular structure of (+)-5-trans Cloprostenol, CAS Number: 57968-81-7
(+)-5-trans Cloprostenol (CAS 57968-81-7)
Alternate Names:
D-Cloprostenol
Application:
(+)-5-trans Cloprostenol is a derivative of prostaglandin F2α
CAS Number:
57968-81-7
Purity:
≥98%
Molecular Weight:
424.9
Molecular Formula:
C22H29ClO6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(+)-5-trans Cloprostenol is a derivative of prostaglandin F2α that has been used as a luteolytic agent for the induction of estrus in animal models and can induce uterin contraction. Although the compound has effectiveness the trans isomer is still 20 times less effective than the cis-isomer during reproductive termination in the hamster model. In a muscle contraction study (+)-5-trans Cloprostenol elicited contraction to horse arterial preparations.
(+)-5-trans Cloprostenol (CAS 57968-81-7) References
- Effect of prostaglandin E2, DL-cloprostenol, and prostaglandin E2 in combination with D-cloprostenol on uterine motility during diestrus in experimental cows. | Hirsbrunner, G., et al. 2003. Anim Reprod Sci. 79: 17-32. PMID: 12853176
- A sheer pharmacologic approach to compare the contractile effects of PGF2alpha, DL-cloprostenol and D-cloprostenol on isolated uterine, tracheal, ileal and arterial smooth muscle preparations. | Beretta, C. and Cavalli, M. 2004. Theriogenology. 62: 837-46. PMID: 15251235
- Intra-vesicle administration of D-cloprostenol for induction of abortion in mid-gestation bitches. | Manca, R., et al. 2008. Anim Reprod Sci. 106: 133-42. PMID: 17521834
- Effects of d-cloprostenol dose and corpus luteum age on ovulation, luteal function, and morphology in nonlactating dairy cows with early corpora lutea. | Valldecabres-Torres, X., et al. 2012. J Dairy Sci. 95: 4389-95. PMID: 22818452
- Effects of d-cloprostenol on different layers and regions of the bovine uterus during the follicular and luteal phases. | Piccinno, M., et al. 2017. Theriogenology. 96: 92-96. PMID: 28532844
- D-Cloprostenol enhances estrus synchronization in tropical hair sheep. | Ramírez, AA., et al. 2018. Trop Anim Health Prod. 50: 991-996. PMID: 29429114
- Cervical penetration rates and efficiency of non-surgical embryo recovery in estrous-synchronized Santa Inês ewes after administration of estradiol ester (benzoate or cypionate) in combination with d-cloprostenol and oxytocin. | Fonseca, JF., et al. 2019. Anim Reprod Sci. 203: 25-32. PMID: 30773245
- Effects of d-cloprostenol administrations with 7.5 and 11.5-day intervals between administrations on pregnancy rates after artificial insemination in estrous cyclic dairy goats. | Bonato, GC., et al. 2019. Anim Reprod Sci. 209: 106172. PMID: 31514929
- Cloprostenol enhances sexual behaviour and semen quality in growing lambs more effectively than Dinoprost. | Sánchez-Dávila, F., et al. 2022. Reprod Domest Anim. 57: 611-615. PMID: 35188980
- Double bond isomers of cloprostenol. | Bowler, J., et al. 1979. Prostaglandins. 17: 789-800. PMID: 504688
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-5-trans Cloprostenol, 1 mg | sc-205139 | 1 mg | $114.00 | |||
(+)-5-trans Cloprostenol, 5 mg | sc-205139A | 5 mg | $520.00 |