5-Chloro-1-phenyl-1H-tetrazole (CAS 14210-25-4)

5-Chloro-1-phenyl-1H-tetrazole (5-CPT) is an organochlorine compound widely utilized in diverse scientific research applications. As a heterocyclic compound with nitrogen and chlorine atoms, it belongs to the tetrazole family. Extensive studies have focused on 5-Chloro-1-phenyl-1H-tetrazole as a model compound to explore the impact of chlorine substitution on the reactivity of nitrogen-containing heterocycles. The scientific research community has employed 5-Chloro-1-phenyl-1H-tetrazole in a range of applications. Notably, it has served as a model compound for investigating the effects of chlorine substitution on the reactivity of nitrogen-containing heterocycles. Furthermore, 5-Chloro-1-phenyl-1H-tetrazole has been employed as a ligand in coordination compound synthesis and as an enzyme inhibitor. While the complete mechanism of action of 5-Chloro-1-phenyl-1H-tetrazole remains unclear, current understanding suggests that the chlorine atom within the molecule acts as a Lewis acid. This Lewis acid forms a covalent bond with the nitrogen atom present in the heterocycle. It is hypothesized that this covalent bond contributes to the heightened reactivity observed in nitrogen-containing heterocycles. In summary, 5-Chloro-1-phenyl-1H-tetrazole, an organochlorine compound, finds widespread application in scientific research. Its membership in the tetrazole family and the presence of nitrogen and chlorine atoms make it a valuable model compound for studying the reactivity effects of chlorine substitution. Additionally, 5-Chloro-1-phenyl-1H-tetrazole acts as a ligand in coordination compound synthesis and an enzyme inhibitor.