Molecular structure of 5-(Bromomethyl)fluorescein, CAS Number: 148942-72-7
5-(Bromomethyl)fluorescein (CAS 148942-72-7)
Alternate Names:
5-BMF
Application:
5-(Bromomethyl)fluorescein is a thiol-reactive fluorescent probe
CAS Number:
148942-72-7
Purity:
≥97%
Molecular Weight:
425.23
Molecular Formula:
C21H13BrO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5-(Bromomethyl)fluorescein is a thiol-reactive fluorescent probe used in labeling of carboxylic acids and nucleotides at the N-atom. 5-(Bromomethyl)fluorescein has been widely used in scientific research for over ten years. It is a photostable compound that can be used to study various biological processes. It has many applications and can be used to detect and quantify proteins, nucleic acids, and other molecules in a variety of biological systems. It is useful for real-time monitoring of the dynamics of biochemical reactions. Researchers have utilized 5-(Bromomethyl)fluorescein to investigate different topics such as protein folding, the binding of proteins to DNA, cell signaling, gene expression, and protein structure and function.
5-(Bromomethyl)fluorescein (CAS 148942-72-7) References
- Metal ion-catalyzed nucleic acid alkylation and fragmentation. | Browne, KA. 2002. J Am Chem Soc. 124: 7950-62. PMID: 12095339
- High-throughput capillary electrophoretic method for determination of total aminothiols in plasma and urine. | Lochman, P., et al. 2003. Electrophoresis. 24: 1200-7. PMID: 12707912
- Universal labeling chemistry for nucleic acid detection on DNA-arrays. | Bernal-Méndez, E., et al. 2003. Nucleosides Nucleotides Nucleic Acids. 22: 1647-9. PMID: 14565486
- Quantification of carboxyl groups in carbodiimide cross-linked collagen sponges. | Everaerts, F., et al. 2007. J Biomed Mater Res A. 83: 1176-1183. PMID: 17595021
- Biomechanical properties of carbodiimide crosslinked collagen: influence of the formation of ester crosslinks. | Everaerts, F., et al. 2008. J Biomed Mater Res A. 85: 547-55. PMID: 17729260
- Pharmacokinetics and organ distribution of fluorescein in experimental pigs: an input study for confocal laser endomicroscopy of the gastrointestinal tract. | Kunes, M., et al. 2010. Neuro Endocrinol Lett. 31 Suppl 2: 57-61. PMID: 21187822
- Fluorescent labeling of membrane proteins on the surface of living cells by a self-catalytic glutathione S-transferase omega 1 tag. | Lee, JJ., et al. 2011. Mol Biosyst. 7: 1270-6. PMID: 21311795
- 5-Bromomethyl fluorescein (5-BMF) for derivatization of carboxyl containing analytes for use with laser-induced fluorescence detection. | Mukherjee, PS., et al. 1995. Pharm Res. 12: 930-6. PMID: 7667203
- Labeling the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum at Glu-439 with 5-(bromomethyl)fluorescein. | Stefanova, HI., et al. 1993. Biochemistry. 32: 6095-103. PMID: 8099497
- Localization of the hinge region of the Ca(2+)-ATPase of sarcoplasmic reticulum using resonance energy transfer. | Baker, KJ., et al. 1994. Biochim Biophys Acta. 1192: 53-60. PMID: 8204650
- Analysis of gamma-(cholesteryloxy)butyric acid in biologic samples by derivatization with 5-(bromomethyl)fluorescein followed by high-performance liquid chromatography with laser-induced fluorescence detection. | Mukherjee, PS. and Karnes, HT. 1996. Anal Chem. 68: 327-32. PMID: 9027240
- An argon-ion laser fluorometer optimal for concentration detection of 5-bromomethyl fluorescein derivatized carboxylic acids | , et al. (1996). Microchimica Acta. volume 124,: pages 99–109.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-(Bromomethyl)fluorescein, 50 mg | sc-214302 | 50 mg | $679.00 |