5-Azido-5-deoxy-3,4-di-O-acetyl-1,2-O-isopropylidene-β-D-fructose (CAS 94801-00-0)

5-Azido-5-deoxy-3,4-di-O-acetyl-1,2-O-isopropylidene-β-D-fructose is a chemically synthesized carbohydrate derivative extensively used in the field of glycoscience, particularly in click chemistry applications for constructing complex glycoconjugates. The azido group in this compound is a reactive functional moiety that enables it to participate in azide-alkyne cycloaddition reactions, a cornerstone of click chemistry, allowing for the creation of stable, covalently linked structures under mild conditions. This property makes it an invaluable tool for modifying carbohydrates and creating novel glycostructures with tailored functionalities. The acetyl and isopropylidene groups serve to protect other functional groups during synthesis and can be selectively removed after the click reaction to reveal the desired functionalities. This chemical′s use is pivotal in the synthesis of glycodrugs and glycomaterials, where precise control over the spatial arrangement of molecules is crucial. In research, it aids in the study of carbohydrate-protein interactions, providing insights into cellular communication and molecular recognition processes. Its role is crucial in advancing the understanding of carbohydrate chemistry, enabling the exploration of new materials and biosensors.