Molecular structure of 4-Nitrophenyl phenylphosphonate, CAS Number: 57072-35-2
4-Nitrophenyl phenylphosphonate (CAS 57072-35-2)
Alternate Names:
4-nitrophenyl hydrogen phenylphosphonate; O-4-nitrophenyl phenylphosphonate
Application:
4-Nitrophenyl phenylphosphonate is a 5′-Nucleotide Phosphodiesterase substrate and Adenosine receptor agonist.
CAS Number:
57072-35-2
Purity:
≥98%
Molecular Weight:
279.19
Molecular Formula:
C12H10NO5P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Nitrophenyl phenylphosphonate is a 5′-Nucleotide Phosphodiesterase substrate.
4-Nitrophenyl phenylphosphonate (CAS 57072-35-2) References
- Nucleophilic displacement on 4-nitrophenyl dimethyl phosphinate by ethoxide ion: alkali metal ion catalysis and mechanism. | Buncel, E., et al. 2004. Org Biomol Chem. 2: 601-10. PMID: 14770240
- Hydrolysis of phosphonate esters catalyzed by 5'-nucleotide phosphodiesterase. | Kelly, SJ., et al. 1975. Biochemistry. 14: 4983-8. PMID: 170964
- Mechanisms of joint neurotoxicity of n-hexane, methyl isobutyl ketone and O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens. | Abou-Donia, MB., et al. 1991. J Pharmacol Exp Ther. 257: 282-9. PMID: 2019992
- 5'-Nucleotide phosphodiesterase: isolation of covalently bound 5'-adenosine monophosphate, an intermediate in the catalytic mechanism. | Landt, M. and Butler, LG. 1978. Biochemistry. 17: 4130-5. PMID: 213103
- Hydrolysis of a phosphonate ester catalyzed by an enzyme from Dictyostelium discoideum. | Rossomando, EF. and Jahngen, JH. 1979. Arch Biochem Biophys. 197: 364-6. PMID: 232405
- Degradation by rat tissues in vitro of organophosphorus esters which inhibit cholinesterase. | Pla, A. and Johnson, MK. 1989. Biochem Pharmacol. 38: 1527-33. PMID: 2719724
- Activation and degradation of the phosphorothionate insecticides parathion and EPN by rat brain. | Forsyth, CS. and Chambers, JE. 1989. Biochem Pharmacol. 38: 1597-603. PMID: 2730675
- The influence of chirality on the delayed neuropathic potential of some organophosphorus esters: neuropathic and prophylactic effects of stereoisomeric esters of ethyl phenylphosphonic acid (EPN oxon and EPN) correlate with quantities of aged and unaged neuropathy target esterase in vivo. | Johnson, MK. and Read, DJ. 1987. Toxicol Appl Pharmacol. 90: 103-15. PMID: 3629585
- 5'-Nucleotide phosphodiesterase: features of the substrate binding site as deduced from specificity and kinetics of some novel substrates. | Landt, M., et al. 1980. Biochemistry. 19: 138-43. PMID: 6243469
- A novel phosphodiesterase I from the soluble fraction of erythrocytes. | Haugen, HF. 1981. Biochim Biophys Acta. 659: 411-21. PMID: 6266489
- A homogeneous cyclic CMP phosphodiesterase hydrolyzes both pyrimidine and purine cyclic 2':3'- and 3':5'-nucleotides. | Helfman, DM. and Kuo, JF. 1982. J Biol Chem. 257: 1044-7. PMID: 6274851
- The catalytic mechanism of bovine intestinal 5'-nucleotide phosphodiesterase. pH and inhibition studies. | Moe, OA. and Butler, LG. 1983. J Biol Chem. 258: 6941-6. PMID: 6304065
- The absorption, distribution, excretion, and metabolism of a single oral dose of O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens. | Abou-Donia, MB., et al. 1983. Toxicol Appl Pharmacol. 70: 18-28. PMID: 6612735
- Differential metabolism of O-ethyl O-4-nitrophenyl phenylphosphonothioate by rat and chicken hepatic microsomes. | Lasker, JM., et al. 1982. Biochem Pharmacol. 31: 1961-7. PMID: 7115416
Activator of:
Adenosine A Receptor.Substrate of:
Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Nitrophenyl phenylphosphonate, 1 g | sc-216989 | 1 g | $245.00 |