Date published: 2025-12-6

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4-Methylumbelliferyl stearate (CAS 79408-85-8)

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Application:
4-Methylumbelliferyl stearate is a substrate for the measurement of lipase activity
CAS Number:
79408-85-8
Molecular Weight:
442.63
Molecular Formula:
C28H42O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Methylumbelliferyl stearate is a substrate for the measurement of lipase activity. it is believed that this compound acts as a substrate for the hydrolysis of esters. This hydrolysis is catalyzed by esterases, which are enzymes that catalyze the hydrolysis of esters to form alcohols and carboxylic acids.


4-Methylumbelliferyl stearate (CAS 79408-85-8) References

  1. Hydrolysis of pyrethroids by human and rat tissues: examination of intestinal, liver and serum carboxylesterases.  |  Crow, JA., et al. 2007. Toxicol Appl Pharmacol. 221: 1-12. PMID: 17442360
  2. Identification, characterization, and expression of a unique secretory lipase from the human pathogen Leishmania donovani.  |  Shakarian, AM., et al. 2010. Mol Cell Biochem. 341: 17-31. PMID: 20349119
  3. Virus-induced atherosclerosis. Herpesvirus infection alters aortic cholesterol metabolism and accumulation.  |  Hajjar, DP., et al. 1986. Am J Pathol. 122: 62-70. PMID: 2934987
  4. A simple, rapid, and sensitive fluorescence-based method to assess triacylglycerol hydrolase activity.  |  Rajan, S., et al. 2021. J Lipid Res. 62: 100115. PMID: 34508728
  5. Hydrolysis of triolein, cholesterol oleate, and 4-methylumbelliferyl stearate by acid and neutral ester hydrolases (lipases) from pigeon adipose tissue: effect of cAMP-dependent protein kinase.  |  Severson, DL., et al. 1981. Can J Biochem. 59: 418-29. PMID: 6271359
  6. Regulation of rat heart triacylglycerol ester hydrolases by free fatty acids, fatty acyl CoA and fatty acyl carnitine.  |  Severson, DL. and Hurley, B. 1982. J Mol Cell Cardiol. 14: 467-74. PMID: 7175949
  7. Effect of chloroquine on rates of lipolysis in the isolated perfused rat heart and in rat epididymal fat pads.  |  Severson, DL., et al. 1980. J Mol Cell Cardiol. 12: 977-92. PMID: 7463488
  8. Characterization of lysosomal acid lipase by site-directed mutagenesis and heterologous expression.  |  Sheriff, S., et al. 1995. J Biol Chem. 270: 27766-72. PMID: 7499245

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Methylumbelliferyl stearate, 100 mg

sc-214257
100 mg
$413.00