Molecular structure of 4-Methylumbelliferyl-α- D-galactopyranoside, CAS Number: 38597-12-5
4-Methylumbelliferyl-α- D-galactopyranoside (CAS 38597-12-5)
See product citations (8)
Alternate Names:
4-Methylumbelliferyl-α- D-galactopyranoside is also known as 4-MU-α-Gal.
Application:
4-Methylumbelliferyl-α- D-galactopyranoside is a fluorogenic substrate for α-galactosidase, used to characterize novel α-galactosidases.
CAS Number:
38597-12-5
Molecular Weight:
338.31
Molecular Formula:
C16H18O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Methylumbelliferyl-α- D-galactopyranoside is a fluorogenic substrate for α-galactosidase, yielding a blue fluorescent solution upon cleavage. 4-Methylumbelliferyl-α- D-galactopyranoside is useful in differentiating species within the family of Enterobacteriaceae and in the localization of α-galactosidase in plants. Fabry disease studies employ 4-Methylumbelliferyl-α- D-galactopyranoside in assays to evaluate α-galactosidase deficiencies. The hydrolysis product of 4-Methylumbelliferyl-α- D-galactopyranoside is 4-MU, with an emission maximum at 445 nm.
4-Methylumbelliferyl-α- D-galactopyranoside (CAS 38597-12-5) References
- Characterization of two alpha-galactosidase mutants (Q279E and R301Q) found in an atypical variant of Fabry disease. | Kase, R., et al. 2000. Biochim Biophys Acta. 1501: 227-35. PMID: 10838196
- Characterization of a galactose specific adhesin of enteroaggregative Escherichia coli. | Grover, V., et al. 2001. Arch Biochem Biophys. 390: 109-18. PMID: 11368522
- Glycosidase profiles of members of the family Enterobacteriaceae. | Kämpfer, P., et al. 1991. J Clin Microbiol. 29: 2877-9. PMID: 1757564
- alpha-Galactosidase activity in human saliva. | Oh, JK., et al. 2008. Arch Oral Biol. 53: 842-8. PMID: 18436191
- β-Galactosidase activity in mixed micelles of imidazolium ionic liquids and sodium dodecylsulfate: A sequential injection kinetic study. | Pinto, PC., et al. 2012. Talanta. 96: 26-33. PMID: 22817923
- Multiplex newborn screening for Pompe, Fabry, Hunter, Gaucher, and Hurler diseases using a digital microfluidic platform. | Sista, RS., et al. 2013. Clin Chim Acta. 424: 12-8. PMID: 23660237
- Further characterization and immunochemical studies on the carbohydrate specificity of jackfruit (Artocarpus integrifolia) lectin. | Ahmed, H. and Chatterjee, BP. 1989. J Biol Chem. 264: 9365-72. PMID: 2722839
- Generation of an in vitro model for peripheral neuropathy in Fabry disease using CRISPR-Cas9 in the nociceptive dorsal root ganglion cell line 50B11. | Kaneski, CR., et al. 2022. Mol Genet Metab Rep. 31: 100871. PMID: 35782611
- Generation of GLA-knockout human embryonic stem cell lines to model peripheral neuropathy in Fabry disease. | Kaneski, CR., et al. 2022. Mol Genet Metab Rep. 33: 100914. PMID: 36092250
- Differential assay for lysosomal alpha-galactosidases in human tissues and its application to Fabry's disease. | Mayes, JS., et al. 1981. Clin Chim Acta. 112: 247-51. PMID: 6263521
- Galectin-1 from bovine spleen: biochemical characterization, carbohydrate specificity and tissue-specific isoform profiles. | Ahmed, H., et al. 1996. J Biochem. 120: 1007-19. PMID: 8982870
- Glycosidases of apple fruit: A multi-functional β-galactosidase | Arthur J. Dick, et al. 1990. Physiologia Plantarum.
- Fluorescent Properties Of Hymecromone And Fluorimetric Analysis Of Hymecromone In Compound Dantong Capsule | Huanhuan Zhi, et al. 2013. Journal of Spectroscopy. 2013.
Substrate of:
alpha-gal A, Enzyme, and Fluorogenic.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Methylumbelliferyl-α- D-galactopyranoside, 50 mg | sc-280454 | 50 mg | $130.00 | |||
4-Methylumbelliferyl-α- D-galactopyranoside, 100 mg | sc-280454A | 100 mg | $193.00 | |||
4-Methylumbelliferyl-α- D-galactopyranoside, 250 mg | sc-280454B | 250 mg | $312.00 | |||
4-Methylumbelliferyl-α- D-galactopyranoside, 500 mg | sc-280454C | 500 mg | $525.00 | |||
4-Methylumbelliferyl-α- D-galactopyranoside, 1 g | sc-280454D | 1 g | $838.00 |