Date published: 2025-9-26

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4-Methylpiperidine (CAS 626-58-4)

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Alternate Names:
4-methylpiperidin
CAS Number:
626-58-4
Purity:
≥98%
Molecular Weight:
99.17
Molecular Formula:
C6H13N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Methylpiperidine is a chemical compound that functions as a building block in the synthesis of various organic compounds. It acts as a nucleophile in organic reactions, participating in the formation of carbon-carbon and carbon-nitrogen bonds. Its mechanism of action involves its ability to undergo nucleophilic substitution reactions, where it can displace other functional groups in organic molecules. This allows for the introduction of the 4-methylpiperidine moiety into the target molecule, enabling the synthesis of more complex organic compounds. 4-methylpiperidine can serve as a precursor in the production of and agrochemicals, contributing to the diversification of chemical libraries for development purposes. Its reactivity and selectivity make it versatile in the construction of molecular scaffolds and the modification of functional groups, supporting the exploration of new chemical entities for various applications.


4-Methylpiperidine (CAS 626-58-4) References

  1. Macrocyclic FKBP51 Ligands Define a Transient Binding Mode with Enhanced Selectivity.  |  Voll, AM., et al. 2021. Angew Chem Int Ed Engl. 60: 13257-13263. PMID: 33843131
  2. Self-Assembled Membrane-like Nanomaterials from Sequence-Defined Peptoid Block Copolymers.  |  Wei, T., et al. 2021. Polymers (Basel). 13: PMID: 34371992
  3. A Shelf Stable Fmoc Hydrazine Resin for the Synthesis of Peptide Hydrazides.  |  Bird, MJ. and Dawson, PE. 2022. Pept Sci (Hoboken). 114: PMID: 36387422
  4. A resorufin-based fluorescence probe for visualizing biogenic amines in cells and zebrafish.  |  Pei, SL., et al. 2022. RSC Adv. 12: 33870-33875. PMID: 36505703
  5. Benzophenone Derivatives with Histamine H3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.  |  Godyń, J., et al. 2022. Molecules. 28: PMID: 36615435
  6. Multitargeting Histamine H3 Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives.  |  Łażewska, D., et al. 2023. Molecules. 28: PMID: 36903593
  7. Self-Assembly and Electrical Conductivity of a New [1]benzothieno[3,2-b][1]-benzothiophene (BTBT)-Peptide Hydrogel.  |  Fortunato, A., et al. 2023. Molecules. 28: PMID: 37049680
  8. Linearization of the Brevicidine and Laterocidine Lipopeptides Yields Analogues That Retain Full Antibacterial Activity.  |  Ballantine, RD., et al. 2023. J Med Chem. 66: 6002-6009. PMID: 37071814
  9. Peptide-Resorcinarene Conjugates Obtained via Click Chemistry: Synthesis and Antimicrobial Activity.  |  Pineda-Castañeda, HM., et al. 2023. Antibiotics (Basel). 12: PMID: 37107135
  10. Triethylamine-Promoted Oxidative Cyclodimerization of 2H-Azirine-2-carboxylates to Pyrimidine-4,6-dicarboxylates: Experimental and DFT Study.  |  Zakharov, TN., et al. 2023. Molecules. 28: PMID: 37298789
  11. Crystal structure of [1,2,4]triazolo[4,3-b]pyridazine derivatives as BRD4 bromodomain inhibitors and structure-activity relationship study.  |  Kim, JH., et al. 2023. Sci Rep. 13: 10805. PMID: 37402749

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Methylpiperidine, 5 ml

sc-238910
5 ml
$23.00

4-Methylpiperidine, 100 ml

sc-238910A
100 ml
$26.00