Molecular structure of 4-Methyl-1-naphthaldehyde, CAS Number: 33738-48-6
4-Methyl-1-naphthaldehyde (CAS 33738-48-6)
CAS Number:
33738-48-6
Molecular Weight:
170.21
Molecular Formula:
C12H10O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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4-Methyl-1-naphthaldehyde is an organic compound found in cigarette smoke and has been identified in the microenvironment surrounding pancreatic cancer cells. it is a precursor to naphthalene, a carcinogen, which undergoes a reaction with ammonium nitrate to form nitrosoamines. Notably, 4-Methyl-1-naphthaldehyde exhibits the ability to inhibit the growth of tumor cells by binding to topoisomerase and hindering DNA synthesis. This molecule′s inhibitory properties on tumor cells may be attributed to its ability to react with amines. Additionally, 4-Methyl-1-naphthaldehyde is a reagent used in the preparation and immunosuppressive activity of lactones through ring-closing metathesis of alkadienes.
4-Methyl-1-naphthaldehyde (CAS 33738-48-6) References
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- Arylthiosemicarbazones as antileishmanial agents. | Manzano, JI., et al. 2016. Eur J Med Chem. 123: 161-170. PMID: 27475107
- Synthesis and Topoisomerase I inhibitory properties of klavuzon derivatives. | Akçok, İ., et al. 2017. Bioorg Chem. 71: 275-284. PMID: 28242062
- Antiproliferative activity of (R)-4'-methylklavuzon on hepatocellular carcinoma cells and EpCAM+/CD133+ cancer stem cells via SIRT1 and Exportin-1 (CRM1) inhibition. | Delman, M., et al. 2019. Eur J Med Chem. 180: 224-237. PMID: 31306909
- A new drug testing platform based on 3D tri-culture in lab-on-a-chip devices. | Gokce, B., et al. 2020. Eur J Pharm Sci. 155: 105542. PMID: 32927074
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Methyl-1-naphthaldehyde, 1 g | sc-226727 | 1 g | $240.00 |