Molecular structure of 4-Methoxydiphenylmethane, CAS Number: 834-14-0
4-Methoxydiphenylmethane (CAS 834-14-0)
Alternate Names:
4-MDM
Application:
4-Methoxydiphenylmethane is an enhancer of LTA4 hydrolase′s aminopeptidase activity
CAS Number:
834-14-0
Molecular Weight:
198.26
Molecular Formula:
C14H14O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
4-Methoxydiphenylmethane is a substrate of LTA4H.
4-Methoxydiphenylmethane (CAS 834-14-0) References
- Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28. | Hulshof, JW., et al. 2005. J Med Chem. 48: 6461-71. PMID: 16190772
- Effect of the leukotriene A4 hydrolase aminopeptidase augmentor 4-methoxydiphenylmethane in a pre-clinical model of pulmonary emphysema. | De Oliveira, EO., et al. 2011. Bioorg Med Chem Lett. 21: 6746-50. PMID: 21983441
- Palladium-catalyzed C(sp3)-H arylation of diarylmethanes at room temperature: synthesis of triarylmethanes via deprotonative-cross-coupling processes. | Zhang, J., et al. 2012. J Am Chem Soc. 134: 13765-72. PMID: 22816972
- Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors. | Calışkan, B. and Banoglu, E. 2013. Expert Opin Drug Discov. 8: 49-63. PMID: 23095029
- Diverse ways of perturbing the human arachidonic acid metabolic network to control inflammation. | Meng, H., et al. 2015. Acc Chem Res. 48: 2242-50. PMID: 26237215
- Ultrapressure liquid chromatography-tandem mass spectrometry assay using atmospheric pressure photoionization (UPLC-APPI-MS/MS) for quantification of 4-methoxydiphenylmethane in pharmacokinetic evaluation. | Farhan, N., et al. 2016. J Pharm Biomed Anal. 128: 46-52. PMID: 27232150
- Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors. | Numao, S., et al. 2017. Sci Rep. 7: 13591. PMID: 29051536
- Proline-Glycine-Proline Peptides Are Critical in the Development of Smoke-induced Emphysema. | Roda, MA., et al. 2019. Am J Respir Cell Mol Biol. 61: 560-566. PMID: 30958968
- Effect of Modifier Structure on the Activation of Leukotriene A4 Hydrolase Aminopeptidase Activity. | Lee, KH., et al. 2019. J Med Chem. 62: 10605-10616. PMID: 31751136
- Substrate-dependent modulation of the leukotriene A4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation. | Lee, KH., et al. 2022. Sci Rep. 12: 9443. PMID: 35676292
Inhibitor of:
Enzyme.Substrate of:
LTA4H.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Methoxydiphenylmethane, 10 g | sc-280444 | 10 g | $191.00 | |||
4-Methoxydiphenylmethane, 50 g | sc-280444A | 50 g | $693.00 |