Date published: 2026-1-20

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4-Iodophenol (CAS 540-38-5)

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Application:
4-Iodophenol is 4-Iodophenol is a chemical used in chemiluminescence imaging assays and experiments, as diagnostic agents in order to detect cancer cells in patients.
CAS Number:
540-38-5
Purity:
≥98%
Molecular Weight:
220.01
Molecular Formula:
C6H5IO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Iodophenol is a halogenated aromatic compound extensively used in organic synthesis and materials research. Its iodine substituent makes it a prime candidate for various cross-coupling reactions, a staple in constructing complex organic molecules. For instance, in Suzuki coupling reactions, 4-Iodophenol can be used to attach phenolic groups to other organic moieties, creating new molecules with potential applications in material sciences and catalysis. The phenol part of the molecule, with its hydroxyl group, also provides an anchor for bonding to metal surfaces or nanoparticles, which is useful in creating advanced functional materials for electronics or photonics. In addition to its role in synthetic chemistry, 4-Iodophenol is often used as a starting material in the synthesis of dyes, pigments, and other compounds where the phenolic structure is a key component in achieving desired properties such as UV stability or fluorescence.


4-Iodophenol (CAS 540-38-5) References

  1. Application of 4-iodophenol-enhanced luminol chemiluminescence to direct detection of horseradish peroxidase encapsulated in liposomes.  |  Kamidate, T., et al. 2009. Anal Sci. 25: 1163-6. PMID: 19745548
  2. Effective processing and evaluation of chemical imaging data with respect to morphological features of the zebrafish embryo.  |  Halbach, K., et al. 2021. Anal Bioanal Chem. 413: 1675-1687. PMID: 33523257
  3. Chlorination decreases acute toxicity of iodophenols through the formation of iodate and chlorinated aliphatic disinfection byproducts.  |  Wang, XS., et al. 2021. Water Res. 194: 116951. PMID: 33640749
  4. Reductive deiodination of 2,4,6-triiodophenol by Vallitalea sp. strain TIP-1 isolated from the marine sponge.  |  Kawamura, Y., et al. 2021. J Biosci Bioeng. 132: 154-160. PMID: 34024749
  5. Formation of iodinated aromatic DBPs at different molar ratios of chlorine and nitrogen in iodide-containing water.  |  Song, H., et al. 2022. Sci Total Environ. 806: 150385. PMID: 34610565
  6. Phenol degradation in waters with high iodide level by layered double hydroxide-peroxodisulfate: Pathways and products.  |  Su, Q., et al. 2022. J Environ Sci (China). 116: 14-24. PMID: 35219412
  7. Organohalide respiration potential in marine sediments from Aarhus Bay.  |  Zhang, C., et al. 2022. FEMS Microbiol Ecol. 98: PMID: 35689665
  8. Room-temperature coalescence of Pd nanoparticles with sacrificial templates and sintering agents, and their catalytic activities in the Suzuki coupling reaction.  |  Okada, S., et al. 2022. RSC Adv. 12: 14535-14543. PMID: 35702252
  9. Metal-free photo-induced sulfidation of aryl iodide and other chalcogenation.  |  Mao, S., et al. 2022. Front Chem. 10: 941016. PMID: 35958235
  10. Facile synthesis of Cu N-lauroyl sarcosinate nanozymes with laccase-mimicking activity and identification of toxicity effects for C. elegans.  |  Meng, F., et al. 2022. RSC Adv. 12: 32898-32902. PMID: 36425211
  11. One-Pot Synthesis of Enzyme and Antibody/CaHPO4 Nanoflowers for Magnetic Chemiluminescence Immunoassay of Salmonella enteritidis.  |  Mao, X. and Ye, R. 2023. Sensors (Basel). 23: PMID: 36904982
  12. Metformin mitigates radiation toxicity exerting antioxidant and genoprotective properties.  |  Karmanova, EE., et al. 2023. Naunyn Schmiedebergs Arch Pharmacol. 1-12. PMID: 36961549
  13. Selective Oxidation of Halophenols Catalyzed by an Artificial Miniaturized Peroxidase.  |  D'Alonzo, D., et al. 2023. Int J Mol Sci. 24: PMID: 37175773

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Iodophenol, 10 g

sc-256780
10 g
$59.00