Date published: 2026-5-30

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(4-Chlorophenyl)triethoxysilane (CAS 21700-74-3)

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Alternate Names:
1-Chloro-4-triethoxysilylbenzene
Application:
(4-Chlorophenyl)triethoxysilane is utilized in Pd-catalyzed cross-coupling
CAS Number:
21700-74-3
Molecular Weight:
274.82
Molecular Formula:
C12H19ClO3Si
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(4-Chlorophenyl)triethoxysilane is a nucleophile that can be utilized in Pd-catalyzed cross-coupling. (4-Chlorophenyl)triethoxysilane is an organosilicon compound. It serves as a valuable reagent in organic synthesis. It acts as a precursor for the synthesis of metal-organic frameworks, playing a role in their formation. Additionally, (4-Chlorophenyl)triethoxysilane demonstrates its significance as a catalyst, driving the creation of metal-organic networks. Beyond its role in synthetic chemistry, it has garnered attention as a biocompatible material and as an inhibitor of protein interactions.


(4-Chlorophenyl)triethoxysilane (CAS 21700-74-3) References

  1. Nickel-Catalyzed Hiyama-type Decarboxylative Coupling of Propiolic Acids and Organosilanes.  |  Edwin Raja, GC., et al. 2016. J Org Chem. 81: 5244-9. PMID: 27188502
  2. Palladium-Catalyzed Hiyama Cross-Couplings of Arylsilanes with 3-Iodoazetidine: Synthesis of 3-Arylazetidines.  |  Liu, Z., et al. 2019. J Org Chem. 84: 12358-12365. PMID: 31532668
  3. Novel Silica Hybrid Xerogels Prepared by Co-Condensation of TEOS and ClPhTEOS: A Chemical and Morphological Study.  |  Cruz-Quesada, G., et al. 2022. Gels. 8: PMID: 36286178
  4. Tuning zinc oxide/organic energy level alignment using mixed triethoxysilane monolayers  |  Brenner, T. M., Chen, G., Meinig, E. P., Baker, D. J., Olson, D. C., Collins, R. T., & Furtak, T. E. 2013. Journal of Materials Chemistry C. 1(37): 5935-5943.
  5. Synthesis of azobenzene substituted tripod-shaped bi (p-phenylene) s. Adsorption on gold and CdS quantum-dots surfaces  |  Hierrezuelo, J., Rico, R., Valpuesta, M., Diaz, A., López–Romero, J. M., Rutkis, M.,.. & Algarra, M. 2013. Tetrahedron. 69(16): 3465-3474.
  6. Changing sandstone rock wettability with supercritical CO2-based silylation  |  Arjomand, E., Easton, C. D., Myers, M., Tian, W., Saeedi, A., & Wood, C. D. 2020. Energy & Fuels. 34(2): 2015-2027.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(4-Chlorophenyl)triethoxysilane, 1 g

sc-252145
1 g
$86.00