Date published: 2026-3-18

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4-Chlorophenyl chloroformate (CAS 7693-45-0)

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Alternate Names:
Chloroformic Acid 4-Chlorophenyl Ester
CAS Number:
7693-45-0
Molecular Weight:
191.01
Molecular Formula:
C7H4Cl2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Chlorophenyl Chloroformate is a highly effective chlorinating agent known to increase the intracellular levels of carbon sources. Shown to act selectively on the phenyl group of histidine and amines. This compound can be used as a synthetic intermediate in the production of various compounds, including antidiabetic agents. Additionally, 4-Chlorophenyl Chloroformate has been used in the preparation of N-hydroxy-N-methylcarbamate 4-chlorophenyl ester.


4-Chlorophenyl chloroformate (CAS 7693-45-0) References

  1. Kinetics and mechanism of the aminolysis of 4-methylphenyl and 4-chlorophenyl 4-nitrophenyl carbonates in aqueous ethanol.  |  Castro, EA., et al. 2003. J Org Chem. 68: 3608-13. PMID: 12713368
  2. Synthesis of Polyanionic Cellulose Carbamates by Homogeneous Aminolysis in an Ionic Liquid/DMF Medium.  |  Bui, CV., et al. 2022. Molecules. 27: PMID: 35209171
  3. Convenient synthesis of poly(γ-benzyl-L-glutamate) from activated urethane derivatives of γ-benzyl-L-glutamate  |  Yasutaka Kamei, Atsushi Nagai, Atsushi Sudo, Haruo Nishida, Kiyoshi Kikukawa, Takeshi Endo. 2008. 46: 2649-2657.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Chlorophenyl chloroformate, 5 g

sc-232607
5 g
$72.00