Molecular structure of 4-Chloro-7-nitrobenzofurazan, CAS Number: 10199-89-0
4-Chloro-7-nitrobenzofurazan (CAS 10199-89-0)
Alternate Names:
NBD-chloride
CAS Number:
10199-89-0
Purity:
≥98%
Molecular Weight:
199.55
Molecular Formula:
C6H2ClN3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Chloro-7-nitrobenzofurazan (4-CNB) is frequently utilized in scientific research, especially within biochemistry and molecular biology. It serves as a reagent in the creation of numerous substances like peptides, nucleosides, and nucleotides. It is a dye that forms highly fluorescent compounds upon reaction with amines or thiol compounds. Therefore, 4-Chloro-7-nitrobenzofurazan acts as a fluorescent marker for proteins and nucleic acids and aids in identifying and measuring small molecules.
4-Chloro-7-nitrobenzofurazan (CAS 10199-89-0) References
- The highly electrophilic character of 4-chloro-7-nitrobenzofurazan and possible consequences for its application as a protein-labelling reagent. | Baines, BS., et al. 1977. Biochem J. 163: 189-92. PMID: 17393
- Allergic contact dermatitis from 4-chloro-7-nitrobenzofurazan. | Brasch, J. 1991. Contact Dermatitis. 25: 121-4. PMID: 1834424
- Molecular structure, vibrational, UV and NBO analysis of 4-chloro-7-nitrobenzofurazan by DFT calculations. | Kurt, M., et al. 2011. Spectrochim Acta A Mol Biomol Spectrosc. 79: 1162-70. PMID: 21571581
- Utility of 4-chloro-7-nitrobenzofurazan for the spectrofluorimetric determination of butylated hydroxyanisole and propyl gallate in foodstuffs. | Chen, M., et al. 2012. J Food Sci. 77: C401-7. PMID: 22394117
- Selective N-terminal fluorescent labeling of proteins using 4-chloro-7-nitrobenzofurazan: a method to distinguish protein N-terminal acetylation. | Bernal-Perez, LF., et al. 2012. Anal Biochem. 428: 13-5. PMID: 22677627
- Utility of 4-chloro-7-nitrobenzofurazan (NBD-CI) for the Spectrophotometric and spectrofluorometric determination of several antihistamine and antihypertensive drugs. | Abd, el-HS., et al. 2013. J AOAC Int. 96: 968-75. PMID: 24282933
- Novel spectrofluorimetric quantification of alogliptin benzoate in biofluids exploiting its interaction with 4-chloro-7-nitrobenzofurazan. | Aref, HA., et al. 2020. Luminescence. 35: 284-291. PMID: 31762136
- Novel spectrofluorimetric quantification of linagliptin in biological fluids exploiting its interaction with 4-chloro-7-nitrobenzofurazan. | Aref, HA., et al. 2020. Luminescence. 35: 626-635. PMID: 31919997
- Utility of 4-chloro-7-nitrobenzofurazan for spectrofluorimetric and spectrophotometric determinations of the anti-hirsutism agent (α-difluoromethylornithine) in pharmaceutical cream samples. | Almahri, A. 2021. Luminescence. 36: 1231-1238. PMID: 33818897
- The interaction of 4-chloro-7-nitrobenzofurazan with Rhodospirillum rubrum chromatophores, their soluble F1-ATPase, and the isolated purified beta-subunit. | Khananshvili, D. and Gromet-Elhanan, Z. 1983. J Biol Chem. 258: 3714-9. PMID: 6219996
- The nature of the reaction of an essential tyrosine residue of bovine heart mitochondrial ATPase with 4-chloro-7-nitrobenzofurazan and related compounds. | Sutton, R. and Ferguson, SJ. 1984. Eur J Biochem. 142: 387-92. PMID: 6235112
- Derivatization with 4-chloro-7-nitrobenzofurazan for liquid chromatographic determination of hydroxyproline in collagen hydrolysate. | Ahnoff, M., et al. 1981. Anal Chem. 53: 485-9. PMID: 7224176
- New reaction of 4-chloro-7-nitrobenzofurazan with amines at high local concentrations. Primitive enzyme models. | Bello, J. and Patrzyc, H. 1980. Int J Pept Protein Res. 15: 464-70. PMID: 7440055
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Chloro-7-nitrobenzofurazan, 1 g | sc-214231 | 1 g | $48.00 | |||
4-Chloro-7-nitrobenzofurazan, 5 g | sc-214231A | 5 g | $140.00 |