Date published: 2026-5-11

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4-Azidobenzaldehyde (CAS 24173-36-2)

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Alternate Names:
p-Azidobenzaldehyde; p-Azido-benzaldehyde
CAS Number:
24173-36-2
Molecular Weight:
147.13
Molecular Formula:
C7H5N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Azidobenzaldehyde is classified as a nitrobenzaldehyde and is used in organic synthesis due to its reactivity. Its reactivity is due to the presence of the azide group, which can be used to form a variety of covalent bonds with other molecules. The azide group can also be used to form a variety of different types of bonds with other molecules, such as carbon-carbon bonds, carbon-nitrogen bonds, and carbon-oxygen bonds. Additionally, It may act to inhibit the enzyme cytochrome P450. It is used as a reagent in organic synthesis, a starting material for the production of pharmaceuticals, a substrate in enzyme assays, and a fluorescent label for biological molecules.


4-Azidobenzaldehyde (CAS 24173-36-2) References

  1. p-Phenylenecarbenonitrene and its halogen derivatives: how does resonance interaction between a nitrene and a carbene center affect the overall electronic configuration?  |  Nicolaides, A., et al. 2001. J Am Chem Soc. 123: 2628-36. PMID: 11456932
  2. Photolysis and oxidation of azidophenyl-substituted radicals: delocalization in heteroatom-based radicals.  |  Serwinski, PR., et al. 2004. J Org Chem. 69: 5247-60. PMID: 15287767
  3. Azido push-pull fluorogens photoactivate to produce bright fluorescent labels.  |  Lord, SJ., et al. 2010. J Phys Chem B. 114: 14157-67. PMID: 19860443
  4. Copper(II)-Catalyzed Conversion of Aryl/Heteroaryl Boronic Acids, Boronates, and Trifluoroborates into the Corresponding Azides: Substrate Scope and Limitations.  |  Grimes, KD., et al. 2010. Synthesis (Stuttg). 2010: 1441-1448. PMID: 20526454
  5. Chemoselective reduction of the carbonyl functionality through hydrosilylation: integrating click catalysis with hydrosilylation in one pot.  |  Roy, SR., et al. 2014. J Org Chem. 79: 9150-60. PMID: 25188382
  6. Easy access to heterobimetallic complexes for medical imaging applications via microwave-enhanced cycloaddition.  |  Desbois, N., et al. 2015. Beilstein J Org Chem. 11: 2202-8. PMID: 26664643
  7. Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.  |  Greene, TF., et al. 2016. J Med Chem. 59: 90-113. PMID: 26680364
  8. Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin.  |  Kuo, TC., et al. 2016. J Med Chem. 59: 8521-34. PMID: 27536893
  9. pH-Responsive Nanoparticles Based on Covalently Grafted Conjugates of Carboxymethyl Chitosan and Daunorubicin for the Delivery of Anti-Cancer Drugs.  |  Cao, J., et al. 2017. J Biomed Nanotechnol. 13: 1647-1659. PMID: 29490753
  10. Synthesis, Structure and In Vitro Cytotoxic Activity of Novel Cinchona-Chalcone Hybrids with 1,4-Disubstituted- and 1,5-Disubstituted 1,2,3-Triazole Linkers.  |  Jernei, T., et al. 2019. Molecules. 24: PMID: 31718009
  11. Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.  |  Park, SJ., et al. 2022. J Med Chem. 65: 3539-3562. PMID: 35077170
  12. Guanidine Derivatives Containing the Chalcone Skeleton Are Potent Antiproliferative Compounds against Human Leukemia Cells.  |  Estévez-Sarmiento, F., et al. 2022. Int J Mol Sci. 23: PMID: 36555165
  13. Photochemical cross-linking of elongation factor G to 70-S ribosomes from Escherichia coli by 4-(6-formyl-3-azidophenoxy)butyrimidate.  |  Maassen, JA. and Möller, W. 1981. Eur J Biochem. 115: 279-85. PMID: 7016534

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Azidobenzaldehyde, 250 mg

sc-503201
250 mg
$357.00

4-Azidobenzaldehyde, 2.5 g

sc-503201A
2.5 g
$2497.00