Date published: 2026-5-2

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4-Aminobiphenyl (CAS 92-67-1)

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Application:
4-Aminobiphenyl is which induces chromosomal instability in human cancer cells
CAS Number:
92-67-1
Molecular Weight:
169.22
Molecular Formula:
C12H11N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Aminobiphenyl induces chromosomal instability in human cancer cells.


4-Aminobiphenyl (CAS 92-67-1) References

  1. Reevaluating cancer risk estimates for short-term exposure scenarios.  |  Halmes, NC., et al. 2000. Toxicol Sci. 58: 32-42. PMID: 11053538
  2. Chromosomal aberrations and SCEs as biomarkers of cancer risk.  |  Norppa, H., et al. 2006. Mutat Res. 600: 37-45. PMID: 16814813
  3. 4-Aminobiphenyl and DNA reactivity: case study within the context of the 2006 IPCS Human Relevance Framework for Analysis of a cancer mode of action for humans.  |  Cohen, SM., et al. 2006. Crit Rev Toxicol. 36: 803-19. PMID: 17118730
  4. Error-Prone and Error-Free Translesion DNA Synthesis over Site-Specifically Created DNA Adducts of Aryl Hydrocarbons (3-Nitrobenzanthrone and 4-Aminobiphenyl).  |  Yagi, T., et al. 2017. Toxicol Res. 33: 265-272. PMID: 29071010
  5. Recent technical and biological development in the analysis of biomarker N-deoxyguanosine-C8-4-aminobiphenyl.  |  Chen, Z., et al. 2018. J Chromatogr B Analyt Technol Biomed Life Sci. 1087-1088: 49-60. PMID: 29709872
  6. Primary aromatic amines and cancer: Novel mechanistic insights using 4-aminobiphenyl as a model carcinogen.  |  Wang, S., et al. 2019. Pharmacol Ther. 200: 179-189. PMID: 31075357
  7. Kartogenin hydrolysis product 4-aminobiphenyl distributes to cartilage and mediates cartilage regeneration.  |  Zhang, S., et al. 2019. Theranostics. 9: 7108-7121. PMID: 31695756
  8. 4-Aminobiphenyl suppresses homologous recombination repair by a reactive oxygen species-dependent p53/miR-513a-5p/p53 loop.  |  Lin, HD., et al. 2020. Toxicology. 444: 152580. PMID: 32905825
  9. Mutagenicity of N-hydroxy-4-aminobiphenyl in human TP53 knock-in (Hupki) mouse embryo fibroblasts.  |  Hölzl-Armstrong, L., et al. 2021. Environ Mol Mutagen. 62: 252-264. PMID: 33620775
  10. Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer.  |  Parsons, R., et al. 1995. Cancer Res. 55: 5548-50. PMID: 7585632

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Aminobiphenyl, 1 g

sc-216773
1 g
$71.00