Date published: 2025-12-17

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4-Aminobenzaldehyde (CAS 556-18-3)

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Alternate Names:
p-Formylaniline
Application:
4-Aminobenzaldehyde is a useful synthetic reagent and monomer
CAS Number:
556-18-3
Molecular Weight:
121.14
Molecular Formula:
C7H7NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Aminobenzaldehyde (4-AB) is a useful synthetic reagent and monomer. It interacts with various proteins, enzymes, and receptors. For example, it inhibits the activity of cyclooxygenase-2 (COX-2), an enzyme involved in inflammation, and tyrosine kinase, an enzyme involved in cell proliferation. In addition, 4-Aminobenzaldehyde may act to inhibit the activity of several other enzymes, including nitric oxide synthase and 5-lipoxygenase. It is an important intermediate in the synthesis of a variety of compounds. Scientific research utilizes 4-Aminobenzaldehyde due to its antioxidant, anti-inflammatory, anti-cancer, and anti-bacterial properties.


4-Aminobenzaldehyde (CAS 556-18-3) References

  1. Structural characterization of pyrrolic cross-links in collagen using a biotinylated Ehrlich's reagent.  |  Brady, JD. and Robins, SP. 2001. J Biol Chem. 276: 18812-8. PMID: 11278513
  2. Chemoselective hydrogenation of nitro compounds with supported gold catalysts.  |  Corma, A. and Serna, P. 2006. Science. 313: 332-4. PMID: 16857934
  3. Preparation of substituted anilines from nitro compounds by using supported gold catalysts.  |  Corma, A. and Serna, P. 2006. Nat Protoc. 1: 2590-5. PMID: 17406513
  4. One-pot organocatalytic asymmetric synthesis of 3-nitro-1,2-dihydroquinolines by a dual-activation protocol.  |  Wang, YF., et al. 2009. Chem Asian J. 4: 1834-1838. PMID: 19830777
  5. A small molecule sensor for fluoride based on an autoinductive, colorimetric signal amplification reaction.  |  Baker, MS. and Phillips, ST. 2012. Org Biomol Chem. 10: 3595-9. PMID: 22456897
  6. Probing the role of surface energetics of electrons and their accumulation in photoreduction processes on TiO₂.  |  Molinari, A., et al. 2014. Chemistry. 20: 7759-65. PMID: 24829086
  7. Coupling Activity-Based Detection, Target Amplification, Colorimetric and Fluorometric Signal Amplification, for Quantitative Chemosensing of Fluoride Generated from Nerve Agents.  |  Sun, X., et al. 2017. Chemistry. 23: 3903-3909. PMID: 28117920
  8. Novel cellulose-based halochromic test strips for naked-eye detection of alkaline vapors and analytes.  |  Abou-Yousef, H., et al. 2017. Talanta. 170: 137-145. PMID: 28501149
  9. A Pd@Zeolite Catalyst for Nitroarene Hydrogenation with High Product Selectivity by Sterically Controlled Adsorption in the Zeolite Micropores.  |  Zhang, J., et al. 2017. Angew Chem Int Ed Engl. 56: 9747-9751. PMID: 28503914
  10. Organically Functionalized Mesoporous SBA-15 Type Material Bearing Fluorescent Sites for Selective Detection of HgII from Aqueous Medium.  |  Paul, L., et al. 2019. ACS Omega. 4: 17857-17863. PMID: 31681894
  11. A new approach for IR spectra matching using normalized local change.  |  Ellis, JD., et al. 2020. Anal Chim Acta. 1103: 49-57. PMID: 32081188
  12. ElNFS1, a nitroreductase gene from Enterobacter ludwigii, confers enhanced detoxification and phytoremediation of 4-nitrobenzaldehyde in rice.  |  Li, Z., et al. 2022. Environ Pollut. 314: 120292. PMID: 36181935

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Aminobenzaldehyde, 5 g

sc-352378
5 g
$217.00

4-Aminobenzaldehyde, 25 g

sc-352378A
25 g
$569.00

Can I get a formal quotation for 25 g x2 for 4-aminobenzaldehyde

Asked by: Busra Kaya
Thank you for contacting Santa Cruz Biotechnology. For a price quote please email scbt@scbt.com.
Answered by: BlakeJ
Date published: 2025-07-23
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Rated 5 out of 5 by from BakerBaker, et al. (PubMed ID 22456897) studied a small molecule sensor for fluoride based on an amplification reaction that results in the product - 4-Aminobenzaldehyde. This product exhibits a yellow signal that can be read colorimetrically. -SCBT Publication Review
Date published: 2015-09-03
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4-Aminobenzaldehyde is rated 5.0 out of 5 by 1.
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