Molecular structure of 4-Amino-6-chloro-1,3-benzenedisulfonamide, CAS Number: 121-30-2
4-Amino-6-chloro-1,3-benzenedisulfonamide (CAS 121-30-2)
Alternate Names:
3-Chloroaniline-4,6-disulfonamide, 4-Amino-6-chlorobenzene-1,3-disulfonamide
Application:
4-Amino-6-chloro-1,3-benzenedisulfonamide is an important target compound useful in long time detection of thiazide diuretics
CAS Number:
121-30-2
Molecular Weight:
285.73
Molecular Formula:
C6H8ClN3O4S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Research shows that 4-amino-6-chloro-1,3-benzenedisulphonamide is an important target compound usufel in long time detection of thiazide diuretics in urine. Has been described as a potent hpCA inhibitor.
4-Amino-6-chloro-1,3-benzenedisulfonamide (CAS 121-30-2) References
- Mass spectrometric behavior of thiazide-based diuretics after electrospray ionization and collision-induced dissociation. | Thevis, M., et al. 2002. Anal Chem. 74: 3802-8. PMID: 12175169
- Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. | Nishimori, I., et al. 2006. Bioorg Med Chem Lett. 16: 2182-8. PMID: 16459077
- Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. | Nishimori, I., et al. 2006. J Med Chem. 49: 2117-26. PMID: 16539401
- Detection of urinary markers for thiazide diuretics after oral administration of hydrochlorothiazide and altizide-relevance to doping control analysis. | Deventer, K., et al. 2009. J Chromatogr A. 1216: 2466-73. PMID: 19187939
- HPLC-photolysis-electrochemical detection in pharmaceutical analysis: application to the determination of spironolactone and hydrochlorothiazide in tablets. | Bachman, WJ. and Stewart, JT. 1990. J Chromatogr Sci. 28: 123-8. PMID: 2273066
- Screening for pharmaceutical transformation products formed in river sediment by combining ultrahigh performance liquid chromatography/high resolution mass spectrometry with a rapid data-processing method. | Li, Z., et al. 2014. Anal Chim Acta. 810: 61-70. PMID: 24439506
- Purification and characterization of carbonic anhydrase from Ağrı Balık Lake trout gill (Salmo trutta labrax) and effects of sulfonamides on enzyme activity. | Demirdag, R., et al. 2015. J Biochem Mol Toxicol. 29: 123-8. PMID: 25345690
- Influence of pH modifiers on the dissolution and stability of hydrochlorothiazide in the bi- and three-layer tablets. | Blatnik, SU., et al. 2015. Acta Pharm. 65: 383-97. PMID: 26677896
- Mechanism for the high bias in the USP colorimetric assay for diazotizable substances in hydrochlorothiazide. | Sieh, DH. and Perlman, S. 1984. J Pharm Sci. 73: 1545-7. PMID: 6394743
- Liquid chromatographic determination of methyldopa and methyldopa-thiazide combinations in dosage forms. | Ting, S. 1983. J Assoc Off Anal Chem. 66: 1436-42. PMID: 6643354
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Amino-6-chloro-1,3-benzenedisulfonamide, 5 g | sc-226484 | 5 g | $40.00 |