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4-Amino-5-bromopyrimidine (CAS 1439-10-7)

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Alternate Names:
5-Bromo-4-pyrimidinylamine
Application:
4-Amino-5-bromopyrimidine is an inhibitor of PD-ECGF (thymidine phosphorylase)
CAS Number:
1439-10-7
Molecular Weight:
174.00
Molecular Formula:
C4H4BrN3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Amino-5-bromopyrimidine is an inhibitor of PD-ECGF (thymidine phosphorylase), an enzyme known to be over-expressed in several tumor types and to play a role in tumor growth and metastasis.


4-Amino-5-bromopyrimidine (CAS 1439-10-7) References

Philip Reigan, Abdul Gbaj, Edwin Chinje, Ian J. Stratford, Kenneth T. Douglas, Sally Freeman, Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase, Bioorganic & Medicinal Chemistry Letters, Volume 14, Issue 21, 1 November 2004, Pages 5247-5250, ISSN 0960-894X, http://dx.doi.org/10.1016/j.bmcl.2004.08.036.

Philip Reigan, Abdul Gbaj, Ian J. Stratford, Richard A. Bryce, Sally Freeman, Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors, European Journal of Medicinal Chemistry, Volume 43, Issue 6, June 2008, Pages 1248-1260, ISSN 0223-5234, http://dx.doi.org/10.1016/j.ejmech.2007.07.015.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Amino-5-bromopyrimidine, 250 mg

sc-394353
250 mg
$69.00

4-Amino-5-bromopyrimidine, 1 g

sc-394353A
1 g
$209.00