Date published: 2025-12-7

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4-Amino-3,5-dichlorobenzoic acid (CAS 56961-25-2)

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CAS Number:
56961-25-2
Molecular Weight:
206.03
Molecular Formula:
C7H5Cl2NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Amino-3,5-dichlorobenzoic acid is a compound utilized in various areas of chemical research, particularly in the synthesis of dyes, polymers, and other organic molecules. The amino group positioned para to the carboxylic acid group allows for facile reactions with electrophiles, making it a useful intermediate in creating amide bonds. The dichloro substitution pattern on the aromatic ring gives this compound distinct electronic properties, influencing its reactivity in electrophilic aromatic substitution reactions. Researchers employ 4-Amino-3,5-dichlorobenzoic acid in the study of aromatic halogenation mechanisms and in the design of molecules that require specific electronic characteristics for their intended applications. Moreover, it serves as a starting material in the production of more complex organic compounds through various organic transformations, such as coupling reactions and nucleophilic substitutions.


4-Amino-3,5-dichlorobenzoic acid (CAS 56961-25-2) References

  1. Specific removal of chlorine from the ortho-position of halogenated benzoic acids by reductive dechlorination in anaerobic enrichment cultures.  |  Gerritse, J., et al. 1992. FEMS Microbiol Lett. 100: 273-80. PMID: 1478462
  2. Improved loading and cleavage methods for solid-phase synthesis using chlorotrityl resins: synthesis and testing of a library of 144 discrete chemicals as potential farnesyltransferase inhibitors.  |  Park, JG., et al. 2004. J Comb Chem. 6: 407-13. PMID: 15132601
  3. Reductive dehalogenations of halobenzoates by anaerobic lake sediment microorganisms.  |  Horowitz, A., et al. 1983. Appl Environ Microbiol. 45: 1459-65. PMID: 16346284
  4. Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome.  |  Richards, S., et al. 2006. Bioorg Med Chem Lett. 16: 6241-5. PMID: 17000111
  5. ssDNA aptamers that recognize diclofenac and 2-anilinophenylacetic acid.  |  Joeng, CB., et al. 2009. Bioorg Med Chem. 17: 5380-7. PMID: 19604698
  6. Aptamers for pharmaceuticals and their application in environmental analytics.  |  Strehlitz, B., et al. 2012. Bioanal Rev. 4: 1-30. PMID: 22389661
  7. Mutagenicity and DNA-damaging potential of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid in vitro.  |  Vulić, A., et al. 2015. Food Chem Toxicol. 77: 82-92. PMID: 25595371
  8. Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors.  |  Valverde, E., et al. 2015. Bioorg Med Chem. 23: 7607-17. PMID: 26596711
  9. Visible-Light-Controlled Histone Deacetylase Inhibitors for Targeted Cancer Therapy.  |  Josa-Culleré, L. and Llebaria, A. 2023. J Med Chem. 66: 1909-1927. PMID: 36654474
  10. Enzyme immunoassay for clenbuterol, an beta 2-adrenergic stimulant.  |  Yamamoto, I. and Iwata, K. 1982. J Immunoassay. 3: 155-71. PMID: 6762380
  11. Comparative metabolism of clenbuterol by rat and bovine liver microsomes and slices.  |  Zalko, D., et al. 1998. Drug Metab Dispos. 26: 28-35. PMID: 9443849

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Amino-3,5-dichlorobenzoic acid, 5 g

sc-277031
5 g
$72.00