4-Amino-2-methylphenylboronic acid, pinacol ester (CAS 631911-01-8)

4-Amino-2-methylphenylboronic acid, pinacol ester, often used in synthetic organic chemistry, is a versatile compound that enables the formation of carbon-boron bonds through boronic ester formation. This particular ester variant, characterized by its pinacol protective group, is pivotal in Suzuki coupling reactions, a cornerstone technique for creating biaryl compounds. The presence of the amino group adjacent to the boronic acid moiety offers a unique electronic and steric environment, which can influence the reactivity and selectivity of the coupling process. This attribute makes it an invaluable tool in the synthesis of complex molecular architectures, often seen in materials science and catalysis research. The pinacol ester group not only enhances the stability of the boronic acid but also improves its solubility in organic solvents, facilitating its handling and reaction conditions. By enabling the construction of carbon-boron bonds under mild conditions, 4-Amino-2-methylphenylboronic acid, pinacol ester, supports the development of novel materials and catalysts, showcasing its significant role in advancing research in organic chemistry and beyond.