4,4′,4′′-Trimethoxytrityl chloride (CAS 49757-42-8)
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4,4′,4′′-Trimethoxytrityl chloride (TMTCl) is an organometallic compound that has been utilized for decades in organic compound synthesis due to its versatility as a reagent. This compound has been utilized in numerous reactions such as the synthesis of peptides, peptoids, other polymers, and heterocyclic compounds including pyridines and quinolines. As a Lewis acid, 4,4′,4′′-Trimethoxytrityl chloride has the ability to interact with various substrates such as amines, alcohols, and carboxylic acids, and can form stable coordination complexes and covalent bonds with substrates resulting in various product formations. Additionally, 4,4′,4′′-Trimethoxytrityl chloride can also form complexes with Lewis bases, such as ethers.
4,4′,4′′-Trimethoxytrityl chloride (CAS 49757-42-8) References
- Two base pair duplexes suffice to build a novel material. | Meng, M., et al. 2009. Chembiochem. 10: 1335-9. PMID: 19422011
- Visible-light-mediated, nitrogen-centered radical amination of tertiary alkyl halides under metal-free conditions to form α-tertiary amines. | Brueckner, AC., et al. 2016. Org Biomol Chem. 14: 4387-92. PMID: 27113972
- Concerning the Role of Supercritical Carbon Dioxide in SN 1 Reactions. | Qiao, YX., et al. 2017. Chemistry. 23: 3898-3902. PMID: 28217900
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4,4′,4′′-Trimethoxytrityl chloride, 2.5 g | sc-238985A | 2.5 g | $57.00 | |||
4,4′,4′′-Trimethoxytrityl chloride, 5 g | sc-238985 | 5 g | $80.00 |