Date published: 2026-5-19

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3α,21-Dihydroxy-5α-pregnan-20-one (CAS 567-02-2)

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Alternate Names:
Allotetrahydrocortexone
CAS Number:
567-02-2
Molecular Weight:
334.49
Molecular Formula:
C21H34O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Positive allosteric modulator of GABAA receptors.


3α,21-Dihydroxy-5α-pregnan-20-one (CAS 567-02-2) References

Burg, et al., Neuroactive steroids induce GABA(A) receptor-mediated depolarizing postsynaptic potentials in hippocampal CA1 pyramidal cells of the rat. Eur. J. Neurosci. 10, 2880, (1998) Zaman, et al., Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid. Eur. J. Pharmacol. 225, 321, (1992) Xue, et al., Partial agonism by 3å,21-dihydroxy-5β-pregnan-20-one at the GABAA receptor neurosteroid site. J. Pharmacol. Exp. Ther. 281, 1095, (1997)

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3α,21-Dihydroxy-5α-pregnan-20-one, 5 mg

sc-252069
5 mg
$225.00