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3-Maleimidopropionic Acid N-Succinimidyl Ester (CAS 55750-62-4)

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Alternate Names:
N-Succinimidyl 3-maleimidopropionate; BMPS; 3-(Maleimido)propionic acid N-hydroxysuccinimide ester
Application:
3-Maleimidopropionic Acid N-Succinimidyl Ester is An amine- and sulfhydryl- reactive heterobifunctional crosslinking reagent, 6.9 angstrom spacer arm
CAS Number:
55750-62-4
Purity:
≥98%
Molecular Weight:
266.21
Molecular Formula:
C11H10N2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Maleimidopropionic Acid N-Succinimidyl Ester has found widespread use for various applications. As a versatile reagent, 3-Maleimidopropionic Acid N-Succinimidyl Ester plays a role in modifying proteins and other molecules, facilitating their covalent labeling. The mechanism of action of 3-Maleimidopropionic Acid N-Succinimidyl Ester hinges on its capacity to form covalent bonds with proteins and other molecules. This binding occurs through the formation of a stable covalent bond between the maleimide group of the 3-Maleimidopropionic Acid N-Succinimidyl Ester molecule and the amino acid side chain of the target molecule. Leveraging this enduring covalent bond, can effectively label proteins and other molecules to enable a multitude of scientific applications.


3-Maleimidopropionic Acid N-Succinimidyl Ester (CAS 55750-62-4) References

  1. A labeling, detection, and purification system based on 4-hydroxyazobenzene-2-carboxylic acid: an extension of the avidin-biotin system.  |  Hofstetter, H., et al. 2000. Anal Biochem. 284: 354-66. PMID: 10964420
  2. Synthesis, characterization, and evaluation of a novel amphiphilic polymer RGD-PEG-Chol for target drug delivery system.  |  Zeng, S., et al. 2014. ScientificWorldJournal. 2014: 546176. PMID: 24578646
  3. DUP1 peptide modified micelle efficiently targeted delivery paclitaxel and enhance mitochondrial apoptosis on PSMA-negative prostate cancer cells.  |  Chen, H., et al. 2016. Springerplus. 5: 362. PMID: 27066372
  4. Synthesis and characterization of a novel methoxy poly(ethylene glycol)-Tat peptide-chitosan copolymers  |  Bo Li, Qing Ma, Gu He, Xiangrong Song, Fengbo Wu, Yu Zheng, Shi Zeng, Chi Liu & Wen Ren. 2013. Colloid and Polymer Science. 291: 1319–1327.
  5. Thiol Michael addition reaction: a facile tool for introducing peptides into polymer-based gene delivery systems  |  Yanping Sun, Hui Liu, Lin Cheng, Shimeng Zhu, Cuifang Cai, Tianzhi Yang, Li Yang, Pingtian Ding. 2018. 67: 25-31.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Maleimidopropionic Acid N-Succinimidyl Ester, 100 mg

sc-206653
100 mg
$146.00

3-Maleimidopropionic Acid N-Succinimidyl Ester, 1 g

sc-206653A
1 g
$464.00

3-Maleimidopropionic Acid N-Succinimidyl Ester, 5 g

sc-206653B
5 g
$1375.00