Date published: 2025-12-8

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3-Fluoro-4-hydroxybenzaldehyde (CAS 405-05-0)

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Alternate Names:
2-Fluoro-4-formylphenol
Application:
3-Fluoro-4-hydroxybenzaldehyde is a chemical intermediate used in the synthesis of various protein inhibitors
CAS Number:
405-05-0
Molecular Weight:
140.11
Molecular Formula:
C7H5FO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Fluoro-4-hydroxybenzaldehyde is focused on organic synthesis and the study of compound reactivity. 3-Fluoro-4-hydroxybenzaldehyde is used for its role as a building block in the synthesis of more complex organic molecules, including ligands and other intermediates that are important in catalytic systems. Some utilize 3-Fluoro-4-hydroxybenzaldehyde to explore its potential in forming Schiff bases, which are useful in various organic transformations. Its properties are examined in hydrogen bonding and electronic effects due to the presence of both electron-donating and electron-withdrawing groups.


3-Fluoro-4-hydroxybenzaldehyde (CAS 405-05-0) References

  1. First dual aromatase-steroid sulfatase inhibitors.  |  Woo, LW., et al. 2003. J Med Chem. 46: 3193-6. PMID: 12852749
  2. Fluoride curcumin derivatives: new mitochondrial uncoupling agents.  |  Ligeret, H., et al. 2004. FEBS Lett. 569: 37-42. PMID: 15225605
  3. Phenolic hydrazones are potent inhibitors of macrophage migration inhibitory factor proinflammatory activity and survival improving agents in sepsis.  |  Dabideen, DR., et al. 2007. J Med Chem. 50: 1993-7. PMID: 17385848
  4. Halogenated analogs of 1'-acetoxychavicol acetate, Rev-export inhibitor from Alpinia galanga, designed from mechanism of action.  |  Tamura, S., et al. 2010. Bioorg Med Chem Lett. 20: 2082-5. PMID: 20219373
  5. Synthesis of a series of caffeic acid phenethyl amide (CAPA) fluorinated derivatives: comparison of cytoprotective effects to caffeic acid phenethyl ester (CAPE).  |  Yang, J., et al. 2010. Bioorg Med Chem. 18: 5032-8. PMID: 20598894
  6. Topical anti-inflammatory activity of boropinic acid and its natural and semi-synthetic derivatives.  |  Epifano, F., et al. 2011. Bioorg Med Chem Lett. 21: 769-72. PMID: 21167711
  7. Synthesis and biological evaluation of 4-phenoxy-6,7-disubstituted quinolines possessing semicarbazone scaffolds as selective c-Met inhibitors.  |  Qi, B., et al. 2013. Arch Pharm (Weinheim). 346: 596-609. PMID: 23843304
  8. Novel arylazoarylmethane as potential inhibitor of macrophage migration inhibitory factor.  |  He, M., et al. 2014. Arch Pharm (Weinheim). 347: 104-7. PMID: 24243226
  9. Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells.  |  Ottanà, R., et al. 2014. Eur J Med Chem. 71: 112-27. PMID: 24287560
  10. Design, synthesis and biological evaluation of novel 4-phenoxy-6,7-disubstituted quinolines possessing (thio)semicarbazones as c-Met kinase inhibitors.  |  Zhai, X., et al. 2016. Bioorg Med Chem. 24: 1331-45. PMID: 26897090
  11. Synthesis and fungicidal activity of novel imidazole-based ketene dithioacetals.  |  Jeanmart, S., et al. 2018. Bioorg Med Chem. 26: 2009-2016. PMID: 29530348
  12. Detection and differentiation of Cys, Hcy and GSH mixtures by 19F NMR probe.  |  Yang, S., et al. 2018. Talanta. 184: 513-519. PMID: 29674077
  13. Design, synthesis, and biological evaluation of novel dual PPARα/δ agonists for the treatment of T2DM.  |  Ren, Q., et al. 2020. Bioorg Chem. 101: 103963. PMID: 32480174
  14. Discovery of novel isoliquiritigenin analogue ISL-17 as a potential anti-gastric cancer agent.  |  Huang, F., et al. 2020. Biosci Rep. 40: PMID: 32515470
  15. Synthesis and biological activity of selenopsammaplin A and its analogues as antitumor agents with DOT1L inhibitory activity.  |  Ju Han, H., et al. 2021. Bioorg Med Chem. 35: 116072. PMID: 33636429

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Fluoro-4-hydroxybenzaldehyde, 1 g

sc-260942
1 g
$32.00

3-Fluoro-4-hydroxybenzaldehyde, 5 g

sc-260942A
5 g
$65.00