3-Deoxy-3-fluoro-D-mannose (CAS 87764-46-3)

3-Deoxy-3-fluoro-D-mannose is a synthetic sugar analog that has gained significant attention in biochemical and pharmaceutical research due to its unique properties and potential applications. One of the primary mechanisms of action of this compound involves its incorporation into glycoconjugates, such as glycoproteins and glycolipids, during cellular metabolism. This altered glycosylation pattern can affect various cellular processes, including cell adhesion, signaling, and recognition. In research settings, 3-Deoxy-3-fluoro-D-mannose has been utilized as a tool to probe the role of specific sugar residues in biological systems, particularly in studies focusing on carbohydrate-protein interactions and the function of glycosyltransferases. Additionally, this compound has been investigated for the development of novel antimicrobial agents targeting bacterial cell wall biosynthesis. Furthermore, 3-Deoxy-3-fluoro-D-mannose derivatives have shown promise as molecular probes for imaging techniques, such as positron emission tomography (PET), enabling the visualization and tracking of glycosylation processes in living organisms. Overall, 3-Deoxy-3-fluoro-D-mannose represents a valuable tool in glycobiology research, offering insights into the roles of carbohydrates in various biological pathways and providing opportunities for the development of diagnostic tools.