Date published: 2025-12-15

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3,5-Dimethyl-1-phenyl-1H-pyrazole (CAS 1131-16-4)

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CAS Number:
1131-16-4
Molecular Weight:
172.23
Molecular Formula:
C11H12N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,5-Dimethyl-1-phenyl-1H-pyrazole, a heterocyclic compound, has garnered attention in scientific research due to its diverse applications. In the realm of organic synthesis, it serves as a fundamental building block for the construction of various heterocyclic compounds. Meanwhile, in biochemistry, 3,5-Dimethyl-1-phenyl-1H-pyrazole has been studied for its potential as an enzyme inhibitor, its ability to interact with DNA, and its impact on protein-protein interactions.


3,5-Dimethyl-1-phenyl-1H-pyrazole (CAS 1131-16-4) References

  1. Structure-Based Design of γ-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors.  |  Ran, X., et al. 2015. J Med Chem. 58: 4927-39. PMID: 26080064
  2. Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases.  |  Krasavin, M., et al. 2017. J Enzyme Inhib Med Chem. 32: 920-934. PMID: 28718328
  3. Synthesis of Unsymmetrical 2,6-Diarylanilines by Palladium-Catalyzed C-H Bond Functionalization Methodology.  |  Kwak, SH., et al. 2018. J Org Chem. 83: 5844-5850. PMID: 29737848
  4. NSC 18725, a Pyrazole Derivative Inhibits Growth of Intracellular Mycobacterium tuberculosis by Induction of Autophagy.  |  Arora, G., et al. 2019. Front Microbiol. 10: 3051. PMID: 32063889
  5. Regiodivergent C-H and Decarboxylative C-C Alkylation by Ruthenium Catalysis: ortho versus meta Position-Selectivity.  |  Korvorapun, K., et al. 2020. Angew Chem Int Ed Engl. 59: 18795-18803. PMID: 32700444
  6. Direct Preparation of N-Substituted Pyrazoles from Primary Aliphatic or Aromatic Amines.  |  Gulia, N., et al. 2021. J Org Chem. 86: 9353-9359. PMID: 34197110
  7. Pyrvinium Pamoate and Structural Analogs Are Early Macrofilaricide Leads.  |  Gunderson, EL., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 35215301
  8. Direct N-heterocyclization of hydrazines to access styrylated pyrazoles: synthesis of 1,3,5-trisubstituted pyrazoles and dihydropyrazoles.  |  Venkateswarlu, V., et al. 2018. RSC Adv. 8: 26523-26527. PMID: 35541044

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,5-Dimethyl-1-phenyl-1H-pyrazole, 5 g

sc-266967
5 g
$78.00