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3,4-Dihydroxybenzylamine hydrobromide (CAS 16290-26-9)

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Alternate Names:
DHBA hydrobromide
CAS Number:
16290-26-9
Molecular Weight:
220.06
Molecular Formula:
C7H9NO2•Hbr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,4-Dihydroxybenzylamine hydrobromide finds versatile applications in scientific research. It has been employed in synthesizing various compounds like 3,4-dihydroxybenzaldehyde, 3,4-dihydroxybenzyl alcohol, and 3,4-dihydroxybenzylamine. Moreover, this compound has been utilized in the production of fluorescent dyes, for biological molecule imaging and detection. As an acid-base catalyst, 3,4-Dihydroxybenzylamine hydrobromide facilitates reactions with other compounds. It also serves as an electron-donating group.


3,4-Dihydroxybenzylamine hydrobromide (CAS 16290-26-9) References

  1. High-performance liquid chromatography with electrochemical detection applied to the analysis of 3,4-dihydroxymethamphetamine in human plasma and urine.  |  Segura, M., et al. 2002. J Chromatogr B Analyt Technol Biomed Life Sci. 769: 313-21. PMID: 11996497
  2. Melanoma cytotoxicity of buthionine sulfoximine (BSO) alone and in combination with 3,4-dihydroxybenzylamine and melphalan.  |  Prezioso, JA., et al. 1992. J Invest Dermatol. 99: 289-93. PMID: 1512464
  3. Effects of tyrosinase activity on the cytotoxicity of 3,4-dihydroxybenzylamine and buthionine sulfoximine in human melanoma cells.  |  Prezioso, JA., et al. 1990. Pigment Cell Res. 3: 49-54. PMID: 2117268
  4. Tumor inhibition and hematological improvements by dopamine analog 3,4-dihydroxybenzylamine in mice bearing transplantable carcinoma.  |  Lahiri, T., et al. 1990. Neoplasma. 37: 387-93. PMID: 2234200
  5. Determination of L-3,4-dihydroxyphenylalanine in blood by high-performance liquid chromatography after solvent extraction.  |  Tsuchiya, H. and Hayashi, T. 1989. J Chromatogr. 491: 291-8. PMID: 2808616
  6. Melanin synthesis and the action of L-dopa and 3,4-dihydroxybenzylamine in human melanoma cells.  |  Kable, EP. and Parsons, PG. 1989. Cancer Chemother Pharmacol. 23: 1-7. PMID: 2909284
  7. Comparison of the inhibitory effects of hydroxyurea, 5-fluorodeoxyuridine, 3,4-dihydroxybenzylamine, and methotrexate on human squamous cell carcinoma.  |  FitzGerald, GB. and Wick, MM. 1987. J Invest Dermatol. 88: 66-70. PMID: 2947954
  8. Antitumor effects of biologic reducing agents related to 3,4-dihydroxybenzylamine: dihydroxybenzaldehyde, dihydroxybenzaldoxime, and dihydroxybenzonitrile.  |  Wick, MM. and FitzGerald, GB. 1987. J Pharm Sci. 76: 513-5. PMID: 3312571
  9. Oxidative Polymerization of 3,4-Dihydroxybenzylamine─The Lower Homolog of Dopamine.  |  Petran, A., et al. 2023. Langmuir. 39: 5610-5620. PMID: 37022985
  10. Potentiation by alpha-difluoromethylornithine of the activity of 3,4-dihydroxybenzylamine, a tyrosinase-dependent melanolytic agent, against B16 melanoma.  |  Prakash, NJ., et al. 1985. Biochem Pharmacol. 34: 1887-90. PMID: 3924051
  11. 3,4-Dihydroxybenzylamine: an improved dopamine analog cytotoxic for melanoma cells in part through oxidation products inhibitory to dna polymerase.  |  FitzGerald, GB. and Wick, MM. 1983. J Invest Dermatol. 80: 119-23. PMID: 6401786
  12. Striatal transporter for dopamine: catechol structure-activity studies and susceptibility to chemical modification.  |  Meiergerd, SM. and Schenk, JO. 1994. J Neurochem. 62: 998-1008. PMID: 8113819
  13. Breakdown of 3,4-dihydroxybenzylamine and dopamine in plasma of various animal species by semicarbazide-sensitive amine oxidase.  |  Boomsma, F., et al. 1993. J Chromatogr. 621: 82-8. PMID: 8308091
  14. Oxidation of 3,4-dihydroxybenzylamine affords 3,4-dihydroxybenzaldehyde via the quinone methide intermediate.  |  Sugumaran, M. 1995. Pigment Cell Res. 8: 250-4. PMID: 8789199
  15. Determination of catecholamines in sheep plasma by high-performance liquid chromatography with electrochemical detection: comparison of deoxyepinephrine and 3,4-dihydroxybenzylamine as internal standard.  |  He, H., et al. 1997. J Chromatogr B Biomed Sci Appl. 701: 115-9. PMID: 9389345

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,4-Dihydroxybenzylamine hydrobromide, 250 mg

sc-232009
250 mg
$34.00

3,4-Dihydroxybenzylamine hydrobromide, 1 g

sc-232009A
1 g
$75.00