Date published: 2025-10-20

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3,4,5-Trimethoxyaniline (CAS 24313-88-0)

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Alternate Names:
3,4,5-Trimethoxybenzenamine
CAS Number:
24313-88-0
Molecular Weight:
183.20
Molecular Formula:
C9H13NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,4,5-Trimethoxyaniline (3,4,5-TMA) is an organic compound characterized by an aromatic ring adorned with three methoxy groups positioned at the 3, 4, and 5 locations. 3,4,5-Trimethoxyaniline has been extensively employed in scientific research. In the realm of organic synthesis, it acts as a building block for constructing intricate molecules. While the complete mechanism of action for 3,4,5-Trimethoxyaniline remains elusive, it is speculated to function as an agonist at specific G protein-coupled receptors. These receptors play a pivotal role in regulating diverse physiological processes like cell proliferation and differentiation. Additionally, 3,4,5-Trimethoxyaniline is believed to exert an influence on the activity of certain enzymes, including cyclooxygenase and lipoxygenase, which participate in the metabolism of fatty acids and other compounds.


3,4,5-Trimethoxyaniline (CAS 24313-88-0) References

  1. Synthesis, biological evaluation and molecular docking investigation of new sulphonamide derivatives bearing naphthalene moiety as potent tubulin polymerisation inhibitors.  |  Wang, G., et al. 2021. J Enzyme Inhib Med Chem. 36: 1402-1410. PMID: 34157927
  2. Discovery of Novel Diarylamide N-Containing Heterocyclic Derivatives as New Tubulin Polymerization Inhibitors with Anti-Cancer Activity.  |  Liu, X., et al. 2021. Molecules. 26: PMID: 34279387
  3. Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation.  |  Dimitrakis, S., et al. 2021. Molecules. 27: PMID: 35011476
  4. Discovery of Novel 3,4-Dihydro-2(1H)-Quinolinone Sulfonamide Derivatives as New Tubulin Polymerization Inhibitors with Anti-Cancer Activity.  |  Ma, J. and Gong, GH. 2022. Molecules. 27: PMID: 35268645
  5. Discovery of novel sulphonamide hybrids that inhibit LSD1 against bladder cancer cells.  |  Liu, J., et al. 2022. J Enzyme Inhib Med Chem. 37: 866-875. PMID: 35350943
  6. Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents.  |  Oliva, P., et al. 2022. Pharmaceutics. 14: PMID: 35745764
  7. Discovery and SAR analysis of phenylbenzo[d][1,3]dioxole-based proprotein convertase subtilisin/kexin type 9 inhibitors.  |  Li, F., et al. 2022. J Enzyme Inhib Med Chem. 37: 2017-2035. PMID: 35854672
  8. Discovery of dual tubulin-NEDDylation inhibitors with antiproliferative activity.  |  Fu, DJ. and Wang, T. 2023. J Enzyme Inhib Med Chem. 38: 166-175. PMID: 36330714
  9. Design, synthesis and biological evaluation of 4-aminoquinoline derivatives as receptor-interacting protein kinase 2 (RIPK2) inhibitors.  |  Fan, T., et al. 2023. J Enzyme Inhib Med Chem. 38: 282-293. PMID: 36408835
  10. Utilization of Supervised Machine Learning to Understand Kinase Inhibitor Toxophore Profiles.  |  Bieberich, AA. and Asquith, CRM. 2023. Int J Mol Sci. 24: PMID: 36982163
  11. CuI-mediated synthesis of 1-aryl-5,6,7-trimethoxybenzimidazoles as potent antitubulin agents.  |  Peng, CM., et al. 2023. RSC Adv. 13: 13169-13176. PMID: 37124006
  12. A Red-Light-Responsive DASA-Polymer with High Water Stability for Controlled Release.  |  Ma, H., et al. 2023. Polymers (Basel). 15: PMID: 37299288
  13. Discovery of a New Chalcone-Trimethoxycinnamide Hybrid with Antimitotic Effect: Design, Synthesis, and Structure-Activity Relationship Studies.  |  Moreira, J., et al. 2023. Pharmaceuticals (Basel). 16: PMID: 37375826

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,4,5-Trimethoxyaniline, 10 g

sc-232042
10 g
$71.00