Date published: 2026-4-24

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3-[2-(4-Fluorophenoxy)ethyl]piperidine

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Molecular Weight:
223.29
Molecular Formula:
C13H18FNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-APB is a transient receptor potential (TRP) activator. The compound also directly blocks the mitochondrial permeability transition pore, sarco/endoplasmic reticulum Ca2+-ATPase pumps, and native store operated channels, as well as other ion channels. 2-APB does not activate the subfamily transient receptor potential vanilloids (TRPVs) TRPV4, TRPV5, and TRPV6, but can activate VR1 (TRPV1), VRL-1 (TRPV2), and TRPV3. 2-ABP was first used as an inhibitor of IP3R (inositol 1,4,5-triphosphate receptor) with the ability to permeate the membrane. 2-ABP can induce Ca2+entry without activating exocytosis. In pancreatic acinar cells 2-ABP can inhibit calcium mobilization. 2-APB is an activator of Orai3.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-[2-(4-Fluorophenoxy)ethyl]piperidine, 500 mg

sc-310653
500 mg
$294.00