Date published: 2026-4-25

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3-(1H-imidazol-1-yl)aniline (CAS 112677-67-5)

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CAS Number:
112677-67-5
Molecular Weight:
159.19
Molecular Formula:
C9H9N3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-(1H-imidazol-1-yl)aniline, an organic compound derived from aniline, finds extensive application in various scientific research fields. Noted for its high stability and low toxicity, it is highly valued in biochemistry, physiology, and pharmacology. This compound serves multiple purposes, serving as a substrate for enzyme assays, an ingredient in fluorescent probes, and a fluorescent tag for protein labeling. Additionally, it contributes to the exploration of protein-protein interactions and aids in the development of novel drug compounds. A distinguishing characteristic of 3-(1H-imidazol-1-yl)aniline lies in its capacity to engage in covalent bonding with proteins. This interaction occurs through a process called Michael addition, involving the formation of a carbon-carbon double bond between the imidazole ring and the protein. This unique attribute enables the compound to function as a fluorescent tag, allowing for precise protein labeling and subsequent in-depth examination.


3-(1H-imidazol-1-yl)aniline (CAS 112677-67-5) References

  1. Discovery of a Diaminopyrimidine FLT3 Inhibitor Active against Acute Myeloid Leukemia.  |  Jarusiewicz, JA., et al. 2017. ACS Omega. 2: 1985-2009. PMID: 28580438
  2. l -(-) -Quebrachitol as a Ligand for Selective Copper(0)-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles.  |  Zhou, Q., et al. 2019. J Org Chem. 84: 8160-8167. PMID: 31190531
  3. Synthesis and Performance of 6FDA-Based Polyimide-Ionenes and Composites with Ionic Liquids as Gas Separation Membranes.  |  O'Harra, KE., et al. 2019. Membranes (Basel). 9: PMID: 31277233
  4. Synthesis and Performance of Aromatic Polyamide Ionenes as Gas Separation Membranes.  |  O'Harra, KE., et al. 2020. Membranes (Basel). 10: PMID: 32235739

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-(1H-imidazol-1-yl)aniline, 250 mg

sc-344059
250 mg
$248.00

3-(1H-imidazol-1-yl)aniline, 1 g

sc-344059A
1 g
$500.00