Date published: 2026-4-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

2-Propylglutaric Acid (CAS 32806-62-5)

0.0(0)
Write a reviewAsk a question

Alternate Names:
2-PGA; 2-Propyl-pentanedioic Acid;
Application:
2-Propylglutaric Acid is a metabolite of Valproic Acid
CAS Number:
32806-62-5
Molecular Weight:
174.19
Molecular Formula:
C8H14O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

2-Propylglutaric acid (2PGA) is a carboxylic acid utilized in scientific research due to its versatile applications. It serves as a vital compound in the metabolism of specific organisms and has garnered interest for its potential in biomedical research. As a naturally occurring, non-toxic acid that can be easily synthesized, 2-Propylglutaric acid has found utility in numerous laboratory experiments, with ongoing exploration of its potential in biomedical research. In scientific research, 2-Propylglutaric acid has been extensively employed in diverse fields such as biochemistry, physiology, and pharmacology. Its applications include investigating the metabolism of various organisms, including humans, and exploring the effects of drugs on the body. Moreover, it has been utilized to study the biochemical and physiological impacts of compounds such as drugs and hormones. Additionally, 2-Propylglutaric acid has been instrumental in studying the effects of environmental pollutants on the body. Significantly, 2-Propylglutaric acid plays a role in the metabolism of specific organisms. It participates in the synthesis of fatty acids and other compounds, as well as the breakdown of proteins and carbohydrates. Additionally, 2-Propylglutaric acid contributes to the production of ATP, the energy currency of cells. It also plays a role in the synthesis of certain hormones, including cortisol.


2-Propylglutaric Acid (CAS 32806-62-5) References

  1. Disposition of valproic acid in maternal, fetal, and newborn sheep. II: metabolism and renal elimination.  |  Kumar, S., et al. 2000. Drug Metab Dispos. 28: 857-64. PMID: 10859160
  2. The effect of valproic acid on hepatic and plasma levels of 15-F2t-isoprostane in rats.  |  Tong, V., et al. 2003. Free Radic Biol Med. 34: 1435-46. PMID: 12757854
  3. In vitro effects of valproate and valproate metabolites on mitochondrial oxidations. Relevance of CoA sequestration to the observed inhibitions.  |  Ponchaut, S., et al. 1992. Biochem Pharmacol. 43: 2435-42. PMID: 1610408
  4. Influence of chronic administration of valproate on ultrastructure and enzyme content of peroxisomes in rat liver and kidney. Oxidation of valproate by liver peroxisomes.  |  Ponchaut, S., et al. 1991. Biochem Pharmacol. 41: 1419-28. PMID: 2018550
  5. Brain metabolomic profiling of eastern honey bee (Apis cerana) infested with the mite Varroa destructor.  |  Wu, JL., et al. 2017. PLoS One. 12: e0175573. PMID: 28403242
  6. Determination of valproic acid and its metabolites by gas chromatography-mass spectrometry with selected ion monitoring.  |  Tatsuhara, T., et al. 1987. J Chromatogr. 399: 183-95. PMID: 3116023
  7. Capillary gas chromatographic assay for valproic acid and its 2-desaturated metabolite in brain and plasma.  |  Semmes, RL. and Shen, DD. 1988. J Chromatogr. 432: 185-97. PMID: 3146579
  8. Determination of valproic acid and its six metabolites in human serum using LC-MS/MS and application to interaction with carbapenems in epileptic patients.  |  Yang, X., et al. 2023. Biomed Chromatogr. 37: e5572. PMID: 36520520
  9. Inhibition of gluconeogenesis by sodium valproate and its metabolites in isolated rat hepatocytes.  |  Rogiers, V., et al. 1985. Xenobiotica. 15: 759-65. PMID: 3934853
  10. Identification of valproic acid metabolites in human serum and urine using hexadeuterated valproic acid and gas chromatographic mass spectrometric analysis.  |  Acheampong, A., et al. 1983. Biomed Mass Spectrom. 10: 586-95. PMID: 6419788
  11. Five doubly unsaturated metabolites of valproic acid in urine and plasma of patients on valproic acid therapy.  |  Kochen, W., et al. 1984. J Clin Chem Clin Biochem. 22: 309-17. PMID: 6429268
  12. Valproic acid and several metabolites: quantitative determination in serum, urine, breast milk and tissues by gas chromatography-mass spectrometry using selected ion monitoring.  |  Nau, H., et al. 1981. J Chromatogr. 226: 69-78. PMID: 6798056
  13. Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers.  |  Watson, DG., et al. 1998. J Pharmacol Exp Ther. 285: 307-16. PMID: 9536026

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Propylglutaric Acid, 2.5 mg

sc-206485
2.5 mg
$296.00

2-Propylglutaric Acid, 5 mg

sc-206485A
5 mg
$510.00

2-Propylglutaric Acid, 10 mg

sc-206485B
10 mg
$920.00