Date published: 2025-10-15

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2-Phenylpropionyl chloride (CAS 22414-26-2)

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Alternate Names:
Hydratropoyl chloride
CAS Number:
22414-26-2
Purity:
≥95%
Molecular Weight:
168.62
Molecular Formula:
C9H9ClO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Phenylpropionyl chloride is a reactive organic compound used in biochemistry for the synthesis of agrochemicals. It is a colorless liquid with a pungent odor, and it is highly reactive due to the presence of the acyl chloride functional group. 2-Phenylpropionyl chloride has ability to undergo acylation reactions with amines, alcohols, and phenols, making it a versatile building block in organic synthesis. In biochemistry, 2-Phenylpropionyl chloride is used as an acylating agent in the preparation of amides, esters, and other derivatives. Its reactivity and selectivity in acylation reactions make it valuable for the modification of biomolecules. 2-Phenylpropionyl chloride has compatibility with a wide range of functional groups, allowing for the efficient and selective modification of complex molecules.


2-Phenylpropionyl chloride (CAS 22414-26-2) References

  1. Catalytic Asymmetric Synthesis of Ketene Heterodimer β-Lactones: Scope and Limitations.  |  Chen, S., et al. 2016. J Org Chem. 81: 7824-37. PMID: 27490092
  2. Chiral spiro phosphoric acid-catalysed enantioselective reaction of ketenes with N-H pyrroles.  |  Wang, QY., et al. 2021. Chem Commun (Camb). 57: 11992-11995. PMID: 34709250
  3. Radical generation enabled by photoinduced N-O bond fragmentation.  |  McClain, EJ., et al. 2022. Chem Sci. 13: 12158-12163. PMID: 36349097
  4. Novel approaches to prodrugs of anticancer diaminodichloroplatinum(II) complexes activated by stereoselective enzymatic ester hydrolysis.  |  Kageyama, Y., et al. 1998. J Inorg Biochem. 70: 25-32. PMID: 9661285
  5. Novel ketene formation by reactions of acid chlorides with low-valent platinum complexes  |  Ishii, Y., Kobayashi, Y., Iwasaki, M., & Hidai, M. 1991. Journal of organometallic chemistry. 405(1): 133-140.
  6. Chromatographic resolution of racemic amines, carboxylic acids, and alcohols by a new homochiral reagent derived fromendo-borneol  |  M. R. Banks, J. I. G. Cadogan, I. M. Dawson, I. Gosney, K. J. Grant, S. Gaur, P. K. G. Hodgson & D. E. Stevenson. 1992. Chromatographia. 34: 48–50.
  7. The Structure of Fortesol, a Novel Fused Tricyclic Alcohol Used for Resolution of Phosphinic and Carboxylic Acids  |  Fortes, A. G., Johnstone, R. A., Whittaker, D., & Lewis, N. J. 1994. The Journal of Organic Chemistry. 59(19): 5836-5837.
  8. Synthesis of 7-substituted dehydronoraporphines, with some biogenetic considerations  |  Atanes, N., Pérez, S., Guitián, E., Castedo, L., & Saá, J. M. 1994. Tetrahedron. 50(38): 11257-11266.
  9. Mesogenic self-assembly of diamides. Crystal structure of a 1, 3-diacylaminobenzene  |  Allouchi, H., Cotrait, M., & Malthěte, J. 2001. Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals. 362(1): 101-110.
  10. 2-Arylpropionyl chlorides in kinetic resolution of racemic 3-methyl-2, 3-dihydro-4 H-[1, 4] benzoxazines  |  Chulakov, E. N., Gruzdev, D. A., Levit, G. L., Sadretdinova, L. S., Krasnov, V. P., & Charushin, V. N. 2011. Russian Chemical Bulletin. 60: 948-954.
  11. Synthesis of Allenyl Esters by Horner–Wadsworth–Emmons Reactions of Ketenes Mediated by Isopropylmagnesium Bromide  |  Sano, S., Matsumoto, T., Yano, T., Toguchi, M., & Nakao, M. 2015. Synlett. 26(15): 2135-2138.
  12. A highly rigid diamine monomer derived from naturally occurring myo‐inositol and its use for polyamide synthesis  |  Sudo, A., & Sugita, S. 2016. Journal of Polymer Science Part A: Polymer Chemistry. 54(21): 3436-3443.
  13. Phosphine-catalyzed stereoselective dimerizations of ketenes  |  Ibrahim, A. A., Wei, P. H., Harzmann, G. D., Nalla, D., Mondal, M., Wheeler, K. A., & Kerrigan, N. J. 2021. Tetrahedron. 78: 131838.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Phenylpropionyl chloride, 1 g

sc-225534
1 g
$55.00