2-Phenyl-4-quinolinol (CAS 1144-20-3)
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2-Phenyl-4-quinolinol (PQ) has garnered significant attention as a synthetic compound. Extensive research has been devoted to exploring the applications of 2-Phenyl-4-quinolinol and its derivatives. Its utility extends to the realm of materials science, where it serves as a fluorescent probe for detecting metal ions and as a building block for synthesizing organic materials. In the field of biochemistry, 2-Phenyl-4-quinolinol has garnered attention for its ability to inhibit various enzymes, including tyrosinase, cholinesterase, and carbonic anhydrase. Tyrosinase, involved in melanin biosynthesis, and cholinesterase, responsible for acetylcholine breakdown, experience inhibited activity in the presence of 2-Phenyl-4-quinolinol. Although the precise mechanism of action of 2-Phenyl-4-quinolinol remains elusive, it is believed to involve enzyme inhibition.
2-Phenyl-4-quinolinol (CAS 1144-20-3) References
- A systematic approach to the optimization of substrate-based inhibitors of the hepatitis C virus NS3 protease: discovery of potent and specific tripeptide inhibitors. | Llinàs-Brunet, M., et al. 2004. J Med Chem. 47: 6584-94. PMID: 15588093
- Alkaloids of Lunasia amara Blanco. 4-Methoxy-2-phenylquinoline | Sidney Goodwin, A. F. Smith, and E. C. Horning, et al. 1957. J. Am. Chem. Soc. 79: 2239–2241.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Phenyl-4-quinolinol, 500 mg | sc-288288 | 500 mg | $204.00 | |||
2-Phenyl-4-quinolinol, 1 g | sc-288288A | 1 g | $338.00 |